Administrative Core

行政核心

• 批准号: 10554361
• 负责人: MANISH J BUTTE
• 金额: $ 19.2万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-24 至 2026-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10554361
• 关键词: Clinical; Clinical Research; Coccidioidomycosis; Communication; Consultations; Databases; Development; Ensure; Expenditure; Fostering; Funding; Genomics; Goals; Group Meetings; Human Resources; Immunogenetics; Immunology; Infrastructure; Institution; Leadership; Mentors; National Institute of Allergy and Infectious Disease; Policies; Principal Investigator; Procedures; Productivity; Publications; Records; Reporting; Research; Resources; Role; Running; Sampling; Scientist; Services; Site; System; Teleconferences; United States National Institutes of Health; Virulence; clinical phenotype; conflict resolution; data sharing; innovation; meetings; organizational structure; programs; research and development; synergism; timeline

Summary This Administrative Core fosters our coalition of clinicians and scientists across the six institutions of our Coccidioidomycosis Collaborative Research Center (CCRC) and aligns our activities to the priorities established by the NIH for this program. To manage our activities, we propose this Administrative Core to interface with each Core and Project and with NIAID/NIH Program Officers. This core will be directed by the UCLA MPI (Butte) and the UCSD MPI (Hoffman), and managed by Alexis Stephens, Clinical Research Coordinator, UCLA Division of Immunology. The administrative duties of this core include management of resources, implementation of policies and best practices, arranging the timely flow of clinical samples, coordination of communications and publications, and storage and sharing of data. The overall goals are to maximize the productive research potential of all Projects and Cores, and ensure the timely completion of goals of this program. In Aim 1, we provide infrastructure support to ensure completion of all research objectives. We will Develop a management plan (leadership and staff), develop an organizational structure and regular meetings, including monthly, quarterly, and Annual Meetings. We will also establish an External Advisory Board in consultation with the NIAID. We will establish a conflict resolution system. We will ensure regulatory compliance and maintain records for all Projects and Cores. An innovative part of this proposal is the development of a LabKey database to track all clinical phenotypes, genomics, and results. Finally, we will ensure close involvement with NIAID. In Aim 2, we provide support for fiscal management and reporting. The Administrative Core will coordinate Principal Investigators and Key Personnel and will organize communications, group meetings, teleconferences, and publications. The Administrative Core will track funds and expenses across all sites In Aim 3, we Establish the Development Research Program, including its administration and the mentoring roles.

总结 这个行政核心促进了我们的六个机构的临床医生和科学家的联盟， 球孢子菌病合作研究中心（CCRC），并调整我们的活动，以确定优先事项 由美国国立卫生研究院为该项目提供。为了管理我们的活动，我们建议这个行政核心与每个 核心和项目，并与NIAID/NIH计划官员。该核心将由UCLA MPI（Butte）指导， UCSD MPI（霍夫曼），并由Alexis Stephens，临床研究协调员，UCLA分部管理。 免疫学。这一核心的行政职责包括管理资源、执行政策 和最佳做法，安排临床样本的及时流动，协调通信， 出版物，以及数据的存储和共享。总体目标是最大限度地提高生产力研究 充分发挥各项目和核心的潜力，确保按时完成本项目的目标。 在目标1中，我们提供基础设施支持，以确保完成所有研究目标。我们将开发 管理计划（领导层和工作人员），制定组织结构和定期会议，包括 每月、每季度和年度会议。我们亦会成立一个外聘顾问委员会， NIAID。我们将建立一个冲突解决机制。我们将确保合规性， 所有项目和核心的记录。该提案的一个创新部分是开发LabKey数据库 跟踪所有临床表型基因组学和结果最后，我们将确保与NIAID密切合作。 在目标2中，我们为财务管理和报告提供支持。行政核心将协调 主要研究者和关键人员，并将组织沟通、小组会议、电话会议， 和出版物。行政核心将跟踪所有地点的资金和支出 在目标3中，我们建立了发展研究计划，包括其管理和指导 角色