Administrative Core
行政核心
基本信息
- 批准号:10554361
- 负责人:
- 金额:$ 19.2万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-01-24 至 2026-12-31
- 项目状态:未结题
- 来源:
- 关键词:ClinicalClinical ResearchCoccidioidomycosisCommunicationConsultationsDatabasesDevelopmentEnsureExpenditureFosteringFundingGenomicsGoalsGroup MeetingsHuman ResourcesImmunogeneticsImmunologyInfrastructureInstitutionLeadershipMentorsNational Institute of Allergy and Infectious DiseasePoliciesPrincipal InvestigatorProceduresProductivityPublicationsRecordsReportingResearchResourcesRoleRunningSamplingScientistServicesSiteSystemTeleconferencesUnited States National Institutes of HealthVirulenceclinical phenotypeconflict resolutiondata sharinginnovationmeetingsorganizational structureprogramsresearch and developmentsynergismtimeline
项目摘要
Summary
This Administrative Core fosters our coalition of clinicians and scientists across the six institutions of our
Coccidioidomycosis Collaborative Research Center (CCRC) and aligns our activities to the priorities established
by the NIH for this program. To manage our activities, we propose this Administrative Core to interface with each
Core and Project and with NIAID/NIH Program Officers. This core will be directed by the UCLA MPI (Butte) and
the UCSD MPI (Hoffman), and managed by Alexis Stephens, Clinical Research Coordinator, UCLA Division of
Immunology. The administrative duties of this core include management of resources, implementation of policies
and best practices, arranging the timely flow of clinical samples, coordination of communications and
publications, and storage and sharing of data. The overall goals are to maximize the productive research
potential of all Projects and Cores, and ensure the timely completion of goals of this program.
In Aim 1, we provide infrastructure support to ensure completion of all research objectives. We will Develop
a management plan (leadership and staff), develop an organizational structure and regular meetings, including
monthly, quarterly, and Annual Meetings. We will also establish an External Advisory Board in consultation with
the NIAID. We will establish a conflict resolution system. We will ensure regulatory compliance and maintain
records for all Projects and Cores. An innovative part of this proposal is the development of a LabKey database
to track all clinical phenotypes, genomics, and results. Finally, we will ensure close involvement with NIAID.
In Aim 2, we provide support for fiscal management and reporting. The Administrative Core will coordinate
Principal Investigators and Key Personnel and will organize communications, group meetings, teleconferences,
and publications. The Administrative Core will track funds and expenses across all sites
In Aim 3, we Establish the Development Research Program, including its administration and the mentoring
roles.
摘要
这一管理核心促进了我们在我们的六个机构的临床医生和科学家的联盟
球孢子菌病合作研究中心(CCRC),并使我们的活动与确定的优先事项保持一致
由美国国立卫生研究院为这个项目。为了管理我们的活动,我们建议此管理核心与每个
核心和项目以及与NIAID/NIH项目官员的合作。这一核心将由加州大学洛杉矶分校MPI(BUTE)和
UCSD MPI(霍夫曼),由加州大学洛杉矶分校临床研究协调员Alexis Stephens管理
免疫学。这一核心的行政职责包括管理资源、执行政策
和最佳做法,安排临床样本的及时流动,协调沟通和
出版物,以及数据的存储和共享。总体目标是最大限度地提高研究成果
评估所有项目和核心的潜力,并确保按时完成本项目的目标。
在目标1中,我们提供基础设施支持,以确保完成所有研究目标。我们将发展
制定管理计划(领导和工作人员),制定组织结构和定期会议,包括
每月、每季度和年度会议。我们还将建立一个外部咨询委员会,与
NIAID。我们将建立冲突解决制度。我们将确保监管合规性并保持
所有项目和核心的记录。这项提议的一个创新部分是开发LabKey数据库
追踪所有的临床表型、基因组学和结果。最后,我们将确保与NIAID密切合作。
在目标2中,我们为财政管理和报告提供支持。行政核心将协调
主要调查员和关键人员,并将组织沟通、小组会议、电话会议、
和出版物。管理核心将跟踪所有站点的资金和支出
在目标3中,我们建立了发展研究计划,包括其管理和指导
角色。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('MANISH J BUTTE', 18)}}的其他基金
Adaptive Immune Dysregulation in Disseminated Coccidioidomycosis
播散性球孢子菌病的适应性免疫失调
- 批准号:
10554381 - 财政年份:2022
- 资助金额:
$ 19.2万 - 项目类别:
Immunoengineering cellobiose as a fuel source for T cells
免疫工程纤维二糖作为 T 细胞的燃料来源
- 批准号:
10661076 - 财政年份:2022
- 资助金额:
$ 19.2万 - 项目类别:
Host Immunogenetics and Fungal Virulence Mechanisms in Coccidioidomycosis
球孢子菌病的宿主免疫遗传学和真菌毒力机制
- 批准号:
10356724 - 财政年份:2022
- 资助金额:
$ 19.2万 - 项目类别:
Host Immunogenetics and Fungal Virulence Mechanisms in Coccidioidomycosis
球孢子菌病的宿主免疫遗传学和真菌毒力机制
- 批准号:
10554360 - 财政年份:2022
- 资助金额:
$ 19.2万 - 项目类别:
Adaptive Immune Dysregulation in Disseminated Coccidioidomycosis
播散性球孢子菌病的适应性免疫失调
- 批准号:
10356729 - 财政年份:2022
- 资助金额:
$ 19.2万 - 项目类别:
Immunoengineering cellobiose as a fuel source for T cells
免疫工程纤维二糖作为 T 细胞的燃料来源
- 批准号:
10539922 - 财政年份:2022
- 资助金额:
$ 19.2万 - 项目类别:
Collaborative multi-site project to speed the identification and management of rare genetic immune diseases
加速罕见遗传免疫疾病的识别和管理的多站点合作项目
- 批准号:
10549340 - 财政年份:2021
- 资助金额:
$ 19.2万 - 项目类别:
Collaborative multi-site project to speed the identification and management of rare genetic immune diseases
加速罕见遗传免疫疾病的识别和管理的多站点合作项目
- 批准号:
10359836 - 财政年份:2021
- 资助金额:
$ 19.2万 - 项目类别:
T-cell Dysfunction as the basis of Disseminated Coccidioidomycosis
T 细胞功能障碍是播散性球孢子菌病的基础
- 批准号:
10338193 - 财政年份:2021
- 资助金额:
$ 19.2万 - 项目类别:
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