The Mayo Clinic NeuroNEXT Clinical Research Site

梅奥诊所 NeuroNEXT 临床研究网站

• 批准号: 10743328
• 负责人: Nathan P Staff
• 金额: $ 46.93万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-15 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10743328
• 关键词: Acceleration; Adult; Applications Grants; Arizona; Awareness; Caring; Child; Clinic; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Communities; Community Trial; Contracts; Country; Diagnosis; Disease; Education; Eligibility Determination; Enrollment; Ensure; Faculty; Florida; Funding Mechanisms; Geography; Goals; Grant; Infrastructure; Institution; Institutional Review Boards; Intervention; Leadership; Life Cycle Stages; Midwestern United States; Minnesota; Mission; Modernization; National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; Neurologic; Neurologist; Neurology; Neurosciences; Participant; Patients; Population; Population Heterogeneity; Positioning Attribute; Principal Investigator; Process; Protocols documentation; Publishing; Rare Diseases; Recording of previous events; Research; Research Personnel; Science; Site; Structure; Therapeutic; Time; Training; Training Programs; Translational Research; Translations; United States; United States National Institutes of Health; Work; career development; clinical center; clinical infrastructure; clinical research site; experience; improved; innovation; member; nervous system disorder; next generation; novel therapeutics; pediatric patients; programs; rare condition; research facility; rural setting; synergism; therapeutic development; trial design

Mayo Clinic, which serves ~1.3M patients annually, has a history of excellence in clinical research and clinical trials. Its state-of-the-art research facilities in Rochester, Minnesota, Jacksonville, Florida, and Scottsdale, Arizona enable coordinated clinical trials in the upper Midwest, Southeast, and Southwest United States. The Department of Neurology, which has over 200 child and adult neurologists, has an enterprise-wide leadership structure that supports its integrated practice, research, and education mission. Mayo Clinic Neurology cares for >90,000 adult and pediatric patients annually and has a robust clinical research enterprise. Departmental faculty have clinical expertise and clinical trial experience across the full spectrum of neurological diseases, including rare and ultra-rare conditions. Mayo Clinic is ideally positioned to provide NeuroNEXT the diverse patients with unmet needs and the clinical trialists with expertise in these diseases. Investigator-initiated clinical trials by Mayo neurology faculty will be directed towards NeuroNEXT funding mechanisms. This grant application aims to support, expand, and innovate neuroscience clinical trial activities at all Mayo Clinic sites by providing the infrastructure to ensure robust integration within NeuroNEXT, while leveraging our institutional strengths. Furthermore, the grant will support an innovative program to train the next generation of clinical trialists to thrive in an evolving landscape of innovative trial design and modern regulatory science.

马约诊所每年为约130万患者提供服务，在临床研究和临床试验方面有着卓越的历史。其在明尼苏达州罗切斯特、佛罗里达的杰克逊维尔和亚利桑那州的斯科茨代尔拥有最先进的研究设施，能够在美国上中西部、东南部和西南部开展协调的临床试验。神经病学系拥有200多名儿童和成人神经学家，拥有全企业的领导结构，支持其综合实践，研究和教育使命。马约临床神经科每年为超过90，000名成人和儿童患者提供护理，并拥有强大的临床研究企业。部门教师在神经系统疾病的全方位临床专业知识和临床试验经验，包括罕见和超罕见的条件。马约诊所是理想的定位，以提供NeuroNEXT的不同患者与未满足的需求和临床试验专家在这些疾病的专业知识。由马约神经病学学院发起的研究者发起的临床试验将直接针对NeuroNEXT资助机制。该拨款申请旨在通过提供基础设施来确保NeuroNEXT内的强大集成，同时利用我们的机构优势，支持、扩展和创新所有马约诊所地点的神经科学临床试验活动。此外，这笔赠款将支持一项创新计划，以培训下一代临床试验人员，使其在创新试验设计和现代监管科学的不断发展中茁壮成长。