Postdoctoral Training Program in Trauma

项目摘要 德克萨斯大学休斯顿健康科学中心（UTHealth）寻求其成功的第四次更新。 多学科博士后Ruth L. Kirschstein国家研究服务奖（NRSA） 研究培训补助金（T32）在伤害和危重病。该培训计划的目标是提供 为创伤博士后提供多学科研究培训，以培养未来的独立调查人员， 将在学术生涯中使用这些技能，增加对创伤性损伤机制的理解， 随后的严重疾病，并告知临床实践。为了实现这些目标，我们的计划招募和 选择有兴趣从事创伤相关研究的博士后候选人 每个日历年的两年期职位。在两年的培训结束时，每个研究员都能够：1） 批判性地分析可用的已发表数据; 2）制定重点假设; 3）设计并执行必要的 实验来检验假设; 4）分析和解释结果，得出适当的结论， 潜在地修改实验策略; 5）有效地提出他们的研究结果口头和在 （1）撰写研究报告;（2）撰写有竞争力的研究报告。在15年中，52%（10/17）的研究员完成了 他们的培训（T32及以后）目前在学术职位，41%已被授予 独立供资;在过去10年中，该奖项产生了208份手稿。自成立以来 2001年，T32培训计划得到了发展，我们提出了新的要素和师资，以促进和集中精力 我们的训练努力。在拟议的方案计划中，我们将重点扩大到以下伤害领域， 危重病：创伤性脑损伤;出血控制和复苏;炎症后果和 器官功能障碍;细胞治疗;和烧伤与每个研究员接受指导，在负责任的行为 研究，再现性，流行病学，生物统计学和信息学与他们的职业目标相一致， 个人发展计划。查尔斯考克斯博士仍然是培训计划的项目主任，他是 由一名新增加的助理主任和一名项目经理协助组成指导委员会。的 领导层接受外部咨询委员会的指导，包括一个小组委员会，以加强 多样性每个学员都被分配到10个主要教师导师中的1个，他们带来了各种专业知识和广泛的 指导经验，并负责确保研究员接受适当的培训， 有效的，道德的，信息丰富的研究项目。资源教员也可协助 在不同于初级导师的专业领域执行项目。最后，扩大评价程序 以改善导师和学员的培训体验。这一全面方法 确保一个全面的，多样化的教师将协助和指导这些年轻的科学家沿着道路， 学术独立性和重大未来的贡献，以照顾受伤的病人。

Project Summary The University of Texas Health Science Center at Houston (UTHealth) seeks a fourth renewal of its successful multidisciplinary postdoctoral Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (T32) in injury and critical illness. The goal of this training program is to provide multidisciplinary research training for postdoctorates in trauma to develop future independent investigators who will use these skills in academic careers that increase understanding of the mechanisms of traumatic injury and subsequent critical illness and to inform clinical practice. To accomplish these goals, our program recruits and selects postdoctoral candidates who are interested in pursuing an academic career in trauma-related research each calendar year for two-year positions. At the end of the two years of training, each fellow is able to: 1) critically analyze available published data; 2) formulate a focused hypothesis; 3) design and perform necessary experiments to test the hypothesis; 4) analyze and interpret results to draw appropriate conclusions and potentially modify experimental strategies; 5) effectively present the results of their research both orally and in writing; and 6) prepare a competitive research proposal. Over 15 years, 52% (10/17) of fellows who completed their training (T32 and subsequent) are currently in academic positions, and 41% have been awarded independent funding; 208 manuscripts have resulted from the award over the past 10 years. Since its creation in 2001, this T32 training program has evolved, and we propose new elements and faculty to advance and focus our training efforts. In the proposed Program Plan, we expand our focus to the following areas in injury and critical illness: Traumatic Brain Injury; Hemorrhage Control and Resuscitation; Inflammatory Consequences and Organ Dysfunction; Cell Therapy; and Bum with each fellow receiving instruction in responsible conduct of research, reproducibility, epidemiology, biostatistics, and informatics in concert with their career goals and Individual Development Plan. Dr. Charles Cox remains the Program Director of the training program, and he is assisted by a newly added Assistant Director and a Program Manager to form the Steering Committee. The leadership receives guidance from an External Advisory Committee, including a sub-committee to enhance diversity. Each trainee is assigned 1 of 10 Primary Faculty Mentors who bring varied expertise and vast mentoring experience and are responsible for ensuring that fellows receive appropriate training to design effective, ethical, and informative research projects. Resource Faculty members are also available to assist in project execution in areas of expertise different from Primary Mentors. Lastly, expanded evaluation procedures are proposed to improve the training experience for both mentors and trainees. This comprehensive approach ensures that a well-rounded, diverse faculty will assist and guide these young scientists along the path to academic independence and significant future contributions to the care of injured patients.