Research Core

研究核心

基本信息

批准号：
10557581
负责人：
Jose Lugo-Martinez
金额：
$ 32.24万
依托单位：
UNIVERSITY OF PUERTO RICO MED SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-19 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10557581
关键词：
Acceleration Address Adoption Area Artificial Intelligence Basic Science Big Data Bioinformatics Biological Biomedical Research Biometry Biostatistics Core Cancer health equity Clinical Research Collaborations Collection Communities Complement Computational Biology Data Data Analyses Data Collection Data Science Databases Development Education Evaluation Experimental Designs Faculty Future Generations Genomics Goals Grant Hispanic Information Services Infrastructure Institution Investments Journals Knowledge Libraries Machine Learning Maintenance Malignant Neoplasms Manuscripts Methodology Outcome Peer Review Pilot Projects Play Population Research Predictive Analytics Predictive Value Publications Publishing Puerto Rico Reproducibility Research Research Design Research Infrastructure Research Personnel Research Project Grants Research Support Research Training Resources Role Semantics Services Software Tools Solid Statistical Data Interpretation System Terminology Training Training and Infrastructure Translational Research Universities analytical method anticancer research application programming interface bioinformatics pipeline computer infrastructure computerized data processing computerized tools data management data quality data repository data resource data sharing genomic data high throughput analysis improved information model interest learning strategy machine learning prediction multiple datasets next generation sequencing novel population based programs research and development syntax tool

项目摘要

PROJECT SUMMARY/ABSTRACT: BIOINFORMATICS AND BIOSTATISTICS (BBC) RESEARCH CORE The Center for the Promotion of Cancer Health Equity (CePCHE) is to provide centralized management, support, specialized technical services, and evaluation for advancing investigators, and creating a sustained integrated basic research development and support center. To accomplish this aim, the CePCHE will establish a much- needed Bioinformatics and Biostatistics Core (BBC) to strengthen and improve the University of Puerto Rico’s (UPR) limited infrastructure in cancer research. The goal of the BBC is to serve as an expert hub to address bioinformatics and biostatistics for the CePCHE’s Research Projects Leaders (RPLs) as well as pipeline and early-stage investigators invested in cancer research. To accomplish this goal, the BBC has established the following specific aims: (1) To implementation, data analysis, provide biostatistical assistance and support for study design methodology, and interpretation of biomedical data; (2) Provide bioinformatics support in predictive analytics (artificial intelligence and machine learning), and computational support (software tools and application programming interfaces or APIs); (3) Establish a computational infrastructure suitable for big-data analyses, and data repository for data collection, curation, annotation, management, and storage of primary and secondary databases; and (4) Establish and strengthen working relationships and a training portfolio of the BBC with other IDeA institutions. Additionally, the BBC will support and train RPLs and other promising junior investigators addressing the CePCHE’s theme in data processing, management, and analysis. The BBC will play a leading role in the creation, collection, and maintenance of a shared Data Repository to expand the immediate access of UPR faculty to these multiple data sets and resources. It is expected that the BBC will provide a solid infrastructure for CePCHE’s RPLs to expedite their research, publish results in a timely manner in high impact peer-reviewed journals, and prepare and submit competitive R-type proposals within three years of initiation of the CePCHE. OMB No. 0925-0001/0002 (Rev. 03/2020 Approved Through 02/28/2023) Page Continuation Format Page

项目摘要/摘要：生物信息学和生物统计学（BBC）研究核心促进癌症卫生平等（CEPCHE）的中心是提供集中的管理，支持，专门的技术服务以及用于推进研究人员的评估，并创建持续的综合基础研究开发和支持中心。为了实现这一目标，Cepche将建立一个很大的需要生物信息学和生物统计学核心（BBC）来加强和改善波多黎各大学 Rico（UPR）有限的癌症研究基础设施。英国广播公司的目标是作为专家枢纽解决Cepche研究项目负责人（RPL）的生物信息学和生物统计学以及管道和早期的研究人员投资了癌症研究。为了实现这一目标，英国广播公司已经建立了以下特定目的：（1）实施，数据分析，为研究设计方法提供生物统计援助和支持，和生物医学数据的解释；（2）在预测分析（人工智能和机器学习）以及计算支持（软件工具和应用程序编程接口或API）; （3）建立适合大数据的计算基础架构分析和数据存储库，用于数据收集，策展，注释，管理和存储主要和存储次要数据库；（4）建立和加强BBC的工作关系和培训组合与其他想法机构。此外，英国广播公司将支持和训练RPL和其他有前途的大三研究人员在数据处理，管理和分析中介绍了Cepche主题。英国广播公司会在共享数据存储库的创建，收集和维护中发挥主导作用，以扩展立即访问UPR教职员工，进入这些多个数据集和资源。预计英国广播公司会为Cepche的RPL提供可靠的基础架构来加快其研究，及时发布结果在高影响同行评审的期刊中，并在三年内准备和提交有竞争力的R型建议 Cepche的启动。 OMB No. 0925-0001/0002（Rev. 03/2020通过02/28/2023批准）页面延续格式页面