Research Core

研究核心

• 批准号: 10557581
• 负责人: Jose Lugo-Martinez
• 金额: $ 32.24万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-19 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10557581
• 关键词: Acceleration; Address; Adoption; Area; Artificial Intelligence; Basic Science; Big Data; Bioinformatics; Biological; Biomedical Research; Biometry; Biostatistics Core; Cancer health equity; Clinical Research; Collaborations; Collection; Communities; Complement; Computational Biology; Data; Data Analyses; Data Collection; Data Science; Databases; Development; Education; Evaluation; Experimental Designs; Faculty; Future; Generations; Genomics; Goals; Grant; Hispanic; Information Services; Infrastructure; Institution; Investments; Journals; Knowledge; Libraries; Machine Learning; Maintenance; Malignant Neoplasms; Manuscripts; Methodology; Outcome; Peer Review; Pilot Projects; Play; Population Research; Predictive Analytics; Predictive Value; Publications; Publishing; Puerto Rico; Reproducibility; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Research Training; Resources; Role; Semantics; Services; Software Tools; Solid; Statistical Data Interpretation; System; Terminology; Training; Training and Infrastructure; Translational Research; Universities; analytical method; anticancer research; application programming interface; bioinformatics pipeline; computer infrastructure; computerized data processing; computerized tools; data management; data quality; data repository; data resource; data sharing; genomic data; high throughput analysis; improved; information model; interest; learning strategy; machine learning prediction; multiple datasets; next generation sequencing; novel; population based; programs; research and development; syntax; tool

PROJECT SUMMARY/ABSTRACT: BIOINFORMATICS AND BIOSTATISTICS (BBC) RESEARCH CORE The Center for the Promotion of Cancer Health Equity (CePCHE) is to provide centralized management, support, specialized technical services, and evaluation for advancing investigators, and creating a sustained integrated basic research development and support center. To accomplish this aim, the CePCHE will establish a much- needed Bioinformatics and Biostatistics Core (BBC) to strengthen and improve the University of Puerto Rico’s (UPR) limited infrastructure in cancer research. The goal of the BBC is to serve as an expert hub to address bioinformatics and biostatistics for the CePCHE’s Research Projects Leaders (RPLs) as well as pipeline and early-stage investigators invested in cancer research. To accomplish this goal, the BBC has established the following specific aims: (1) To implementation, data analysis, provide biostatistical assistance and support for study design methodology, and interpretation of biomedical data; (2) Provide bioinformatics support in predictive analytics (artificial intelligence and machine learning), and computational support (software tools and application programming interfaces or APIs); (3) Establish a computational infrastructure suitable for big-data analyses, and data repository for data collection, curation, annotation, management, and storage of primary and secondary databases; and (4) Establish and strengthen working relationships and a training portfolio of the BBC with other IDeA institutions. Additionally, the BBC will support and train RPLs and other promising junior investigators addressing the CePCHE’s theme in data processing, management, and analysis. The BBC will play a leading role in the creation, collection, and maintenance of a shared Data Repository to expand the immediate access of UPR faculty to these multiple data sets and resources. It is expected that the BBC will provide a solid infrastructure for CePCHE’s RPLs to expedite their research, publish results in a timely manner in high impact peer-reviewed journals, and prepare and submit competitive R-type proposals within three years of initiation of the CePCHE. OMB No. 0925-0001/0002 (Rev. 03/2020 Approved Through 02/28/2023) Page Continuation Format Page

项目摘要/摘要：生物信息学与生物统计学（bbc）研究核心