课题基金 / 基金详情

SERUM AMYLOID A PROTEIN--ROLE IN ATHEROGENESIS

SERUM AMYLOID A PROTEIN--ROLE IN ATHEROGENESIS
血清淀粉样蛋白 A——在动脉粥样硬化形成中的作用
批准号:
2052116
负责人:
FREDERICK C. DE BEER
金额:
$16.66万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1994
资助国家:
美国
项目状态:
已结题
起止时间:
1994-08-10 至 1999-07-31

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DESCRIPTION (Adapted from Applicant's Abstract): This proposal addresses the thesis that chronic inflammatory diseases - common in an ageing population - accelerates the development of atherosclerosis. During the acute phase response, serum amyloid A protein (A-5A-A>, an apolipoprotein, increases 1,000 fold and becomes a major component of high density lipoprotein (HDL). In spite of intense modern interest in the HDL particle, the teleological role of this alteration of HDL apolipoprotein composition during inflammation is unknown. The investigators propose that A-SAA mediate the remodelling of HDL to accommodate a modified physiological requirement for this particle during
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Serum Amyloid A, Inflammasome Activation, and Abdominal Aortic Aneurysms
  • 批准号:
    9213910
  • 项目类别:
  • 资助金额:
    $52.63万
  • 财政年份:
    2017
  • 负责人:
    FREDERICK C. DE BEER
  • 依托单位:
HDL Structure and Metabolism During Inflammation
  • 批准号:
    7219726
  • 项目类别:
  • 资助金额:
    $32.69万
  • 财政年份:
    2006
  • 负责人:
    FREDERICK C. DE BEER
  • 依托单位:
Analytical and Preparative Core
  • 批准号:
    7219730
  • 项目类别:
  • 资助金额:
    $21.92万
  • 财政年份:
    2006
  • 负责人:
    FREDERICK C. DE BEER
  • 依托单位:
SR-BI MEDIATED SELECTIVE CHOLESTEROL ESTER UPTAKE
  • 批准号:
    6509679
  • 项目类别:
  • 资助金额:
    $22.05万
  • 财政年份:
    2001
  • 负责人:
    FREDERICK C. DE BEER
  • 依托单位:
海外基金