Innovative NextGen pig breeding using DNA sequence data

使用 DNA 序列数据的创新下一代猪育种

• 批准号: 102271
• 金额: $ 60.58万
• 依托单位: PIG IMPROVEMENT COMPANY UK LIMITED
• 依托单位国家: 英国
• 项目类别: BEIS-Funded Programmes
• 财政年份: 2015
• 资助国家: 英国
• 起止时间: 2015 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=102271
• 关键词: Innovative; NextGen; pig; breeding; using

This Project addresses food security and sustainability by substantially increasing the efficiency of genomic selection of pigs. Specifically we will develop a new technology we call NextGen Breeding, based on the collection and utilization of very large quantities of sequence data, which will enable us to dramatically accelerate the rate of genetic improvement in our pig populations. The project involves collaboration between two world class UK partners, PIC (part of Genus plc), the world’s leading pig breeding company and The Roslin Institute (RI), the world’s leading research centre in the application of genomics and quantitative genetics to farm animal breeding. The project requires whole genome sequencing of samples on an unprecedented scale and even though our innovative approach dramatically reduces the costs over the conventional paradigm, the risk and costs are still considerable.

该项目通过大幅提高猪的基因组选择效率来解决粮食安全和可持续性问题。具体地说，我们将开发一种名为NextGen育种的新技术，基于大量序列数据的收集和利用，这将使我们能够显著加快我们猪种群的遗传改良速度。该项目涉及两个世界级的英国合作伙伴之间的合作：世界领先的生猪养殖公司PIC(Genus plc的一部分)和世界领先的将基因组学和数量遗传学应用于农场动物育种的研究中心罗斯林研究所(RI)。该项目需要以前所未有的规模对样本进行全基因组测序，尽管我们的创新方法大大降低了传统模式的成本，但风险和成本仍然相当可观。