REACTION INTERMEDIATE ANALOGS OF CARNITINE ACYL TRANSFER

肉碱酰基转移的反应中间体类似物

• 批准号: 2181180
• 负责人: RICHARD David GANDOUR
• 金额: $ 8.7万
• 依托单位: VIRGINIA POLYTECHNIC INST AND ST UNIV
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-01-01 至 1996-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2181180
• 关键词: REACTION; INTERMEDIATE; ANALOGS; CARNITINE; ACYL

项目成果

Stereoisomeric acylamidomorpholinium carnitine analogues: selective inhibitors of carnitine palmitoyltransferase I and II.

• DOI: 10.1016/s0960-894x(99)00543-0
• 发表时间: 1999-11
• 期刊: Bioorganic & medicinal chemistry letters
• 影响因子: 2.7
• 作者: P. S. Savle;S. Pande;T. S. Lee;R. Gandour

Methyl (2S,6S:2R,6R)-6-(2-cyanoethyl)-4,6-dimethyl-2-morpholineacetate.

(2S,6S:2R,6R)-6-(2-氰基乙基)-4,6-二甲基-2-吗啉乙酸甲酯。

• DOI: 10.1107/s0108270194003604
• 发表时间: 1995
• 期刊: Acta crystallographica. Section C, Crystal structure communications
• 作者: Sun,G;Fronczek,FR;Gandour,RD
• 通讯作者: Gandour,RD

2,6,6-Trimethyl-2-oxo-1,3-dioxa-6-azonia-2-phosphocyclooctane iodide.

2,6,6-三甲基-2-氧代-1,3-二氧杂-6-氮氮-2-磷酸环辛烷碘化物。

• DOI: 10.1107/s0108270195003556
• 发表时间: 1995
• 期刊: Acta crystallographica. Section C, Crystal structure communications
• 作者: Kumaravel,G;Gandour,RD;Fronczek,FR
• 通讯作者: Fronczek,FR

Inhibition of acetylcholinesterase by hemicholiniums, conformationally constrained choline analogues. Evaluation of aryl and alkyl substituents. Comparisons with choline and (3-hydroxyphenyl)trimethylammonium.

半胆碱盐（构象受限的胆碱类似物）对乙酰胆碱酯酶的抑制。

• DOI: 10.1021/tx00027a015
• 发表时间: 1992
• 期刊: Chemical research in toxicology
• 影响因子: 4.1
• 作者: Lee,BH;Stelly,TC;Colucci,WJ;Garcia,JG;Gandour,RD;Quinn,DM
• 通讯作者: Quinn,DM

Intramolecular hemiacetals. The acid-base-catalyzed ring-chain interconversion of 2-substituted 2-hydroxy-4,4-dimethylmorpholinium cations in aqueous solution.

分子内半缩醛。

• DOI: 10.3891/acta.chem.scand.45-0558
• 发表时间: 1991
• 期刊: Acta chemica Scandinavica (Copenhagen, Denmark : 1989)
• 作者: Sørensen,PE;McClelland,RA;Gandour,RD
• 通讯作者: Gandour,RD