Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing

通过等离子体介导的气体传感进行早期医学诊断

• 批准号: DP150101939
• 负责人: Prof Antonio Tricoli
• 金额: $ 29.94万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-06-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP150101939
• 关键词: Early; Stage; Medical; Diagnostics; Plasmon

This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanoparticles with well-defined light absorption properties will be fabricated. Superior selectivity will be achieved by matching the wavelength of the absorbed light with the required activation energy for oxidation/reduction. Successful outcomes will enable multi-analyte fingerprint identification by on-chip devices with applications ranging from portable medical diagnostics to national security.

该项目将研究利用金属纳米结构中的等离子体对光的吸收来激活半导体纳米颗粒上气体分子的选择性氧化/还原。这一概念将被用于开发一种能够测量用于肺癌检测的超低浓度(Ppb)呼吸标志物的传感技术。有望制备出具有良好光吸收性能的半导体和金属纳米多孔传感薄膜。通过将吸收光的波长与氧化/还原所需的激活能相匹配，将获得优异的选择性。成功的结果将使芯片设备能够进行多分析物指纹识别，应用范围从便携式医疗诊断到国家安全。