ROTATIONAL RESONANCE NMR STRUCTURAL STUDIES OF RECEPTORS

受体的旋转共振核磁共振结构研究

• 批准号: 2184217
• 负责人: STEVEN Owen SMITH
• 金额: $ 10万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-15 至 1996-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2184217
• 关键词: nuclear magnetic resonance spectroscopy; protein structure; receptor

This is a Shannon Award providing partial support for research projects that fall short of the assigned institute's funding range but are in the margin of excellence. The Shannon award is intended to provide support to test the feasibility of the approach; develop further tests and refine research techniques; perform secondary analysis of available data sets; or conduct discrete projects that can demonstrate the PI's research capabilities or lend additional weight to an already meritorious application. Further scientific data for the CRISP System are unavailable at this time.

这是香农奖，为研究项目提供部分支持

项目成果

Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer.

• DOI: 10.1016/s1097-2765(03)00389-7
• 发表时间: 2003-11
• 期刊: Molecular cell
• 影响因子: 16
• 作者: Nadine Seubert;Yohan Royer;J. Staerk;K. Kubatzky;V. Moucadel;Shyam S. Krishnakumar;Steven O. Smith

Structural models of the bovine papillomavirus E5 protein

牛乳头瘤病毒E5蛋白的结构模型

• 发表时间: 1998
• 期刊: Proteins: Structure, Function, and Bioinformatics
• 作者: Toral Surti;O. Klein;K. Aschheim;D. DiMaio;Steven O. Smith
• 通讯作者: Steven O. Smith

High-resolution 1H MAS RFDR NMR of biological membranes.

• DOI: 10.1016/j.jmr.2008.12.009
• 发表时间: 2009-03
• 期刊: Journal of magnetic resonance (San Diego, Calif. : 1997)
• 作者: Aucoin D;Camenares D;Zhao X;Jung J;Sato T;Smith SO
• 通讯作者: Smith SO

Transmembrane interactions in the activation of the Neu receptor tyrosine kinase.

Neu 受体酪氨酸激酶激活中的跨膜相互作用。

• DOI: 10.1021/bi012117l
• 发表时间: 2002
• 期刊: Biochemistry
• 影响因子: 2.9
• 作者: Smith,StevenO;Smith,Charles;Shekar,Srinivasan;Peersen,Olve;Ziliox,Martine;Aimoto,Saburo
• 通讯作者: Aimoto,Saburo

EGFR juxtamembrane domain, membranes, and calmodulin: kinetics of their interaction.

• DOI: 10.1016/j.bpj.2009.03.027
• 发表时间: 2009-06
• 期刊: Biophysical journal
• 影响因子: 3.4
• 作者: P. Sengupta;Eran Bosis;E. Nachliel;M. Gutman;Steven O. Smith;G. Mihalyne;I. Zaitseva;S. McLaughlin