ISOLATION AND PURIFICATION OF MICHELLAMINE B

米糠胺 B 的分离纯化

• 批准号: 2108337
• 负责人: M LALITH KUMAR
• 金额: $ 7.22万
• 依托单位: THAR TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-01 至 1995-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2108337
• 关键词: alkaloids; atmospheric pressure; carbon dioxide; density; dimer; high performance liquid chromatography; isomer; isoquinolines; methanol; method development; monomer; solvent extraction; solvents; stereochemistry; temperature

Thar Designs proposes to use supercritical fluid extraction (SFE) to extract michellamine from the plant material Anistrocladus korupensis. Thar Designs also proposes to separate the monomers and the dimers by manipulating the pressure and temperature of the extraction. To separate michellamin A from B, Thar has proposed two unique solutions that have not been tried earlier. One would be using a unique stereospecific probe and the other is to use a chromatographic technique. We believe that at least one of them would work for sure.

THAR设计建议使用超临界流体提取（SFE） 从植物材料Anistrocladus korupensis中提取米其胺。 Thar设计还建议将单体和二聚体分开 操纵提取的压力和温度。 分开 塔尔（Thar 没有早些时候尝试。 一种将使用独特的立体特异性探针 另一种是使用色谱技术。 我们相信 他们中至少有一个人肯定会起作用。