3D STEREO AIDS TO STEREOTACTIC CANCER BRAIN SURGERY

3D 立体辅助立体定向癌症脑部手术

• 批准号: 2270910
• 负责人: LESLIE M ARMINSKI
• 金额: $ 6.86万
• 依托单位: POTOMAC MEDICAL SYSTEMS
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-08-01 至 1995-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2270910
• 关键词: biomedical equipment development; brain imaging /visualization /scanning; neoplasm /cancer surgery; neurosurgery; stereotaxic techniques; ultrasonography

It is very important to develop a simple, safe, and reliable system for coordinating cancer brain surgery while it is actually being done. This is true for simple stereotactic techniques and also true for resections. Currently there are a number of devices that allow integration of pre- operative stereotactic coordinates to intra-operative use. This allows tumor localization and a high degree of accuracy, at least at the beginning of surgery. The major problem is that as the surgery proceeds, and as the brain either relaxes or swells, and as some tumor is removed, the coordinates change. In this regard, it would be nice to have ultrasound guidance during the operation which was initially coordinated with stereotactic information derived from 3-D stereo computer reconstruction with prior MRI or CT scans in stereotactic space. But, in fact, the use of ultrasound is probably the only way of carrying out this real-time, on-line guidance, since the use of both CT and MRI for this purpose would be unfeasible froth both a physical and financial viewpoint. In addition, CT would involve x-ray exposures, and MRI presents a strong magnetic field and would require the use of only non- magnetic metallic instrumentation. On the other hand, the ultrasound probe can easily be placed on the brain, either through an adjacent hole in the skull or through the surgical brain access.

开发一种简单、安全、可靠的系统， 协调癌症脑手术的同时，它实际上正在做。 这 对于简单的立体定向技术是正确的，对于切除术也是正确的。 目前，有许多设备允许集成预处理， 手术立体定向坐标到术中使用。 这允许 肿瘤定位和高度的准确性，至少在 手术的开始。 主要的问题是随着手术的进行， 随着大脑的放松或膨胀，随着肿瘤的切除， 坐标就变了 在这方面，如果能有一个 手术期间的超声引导，最初协调 通过三维立体计算机获得的立体定向信息 在立体定向空间中使用先前MRI或CT扫描进行重建。 但是， 事实上，使用超声波可能是唯一的方法， 这种实时，在线指导，因为使用CT和MRI 这一目的在物质和财政上都是不可行的。 观点 此外，CT将涉及X射线曝光，而MRI 提供了一个强大的磁场，将需要使用只有非- 磁性金属仪器 另一方面，超声波 探针可以很容易地放置在大脑上，或者通过相邻的孔， 或者通过外科手术的脑部通道