IBEX Enhanced X-ray Mammography

IBEX 增强型 X 射线乳腺摄影

• 批准号: 105204
• 金额: $ 89.3万
• 依托单位: IBEX INNOVATIONS LTD
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=105204
• 关键词: IBEX; Enhanced; ray; Mammography

"The project will develop and commercialise novel technologies to radically improve the safety, effectiveness and patient comfort of X-ray breast imaging.Firstly, the project will adapt the IBEX Trueview(r) gridless scatter correction method for use in mammography and Digital Breast Tomosynthesis (DBT) systems and demonstrate its effectiveness to reduce patient dose and improve image quality in mammograms and DBT reconstructions. The in-vivo and ex-vivo data generated during this initial phase will be used to market the capability to leading medical X-ray system integrators and secure commercial licence deals within the first year of the project.Secondly, the project will develop and demonstrate the effectiveness of a prototype 3D X-ray imaging system capable of creating full, high-contrast 3D reconstructions of uncompressed breasts at less patient dose than a standard 2D mammogram and without injected contrast agents. This radical new product has the potential to transform breast screening and cancer diagnosis, especially for women with dense breasts. The ex-vivo data collected during this second phase will be used to inform a commercialisation strategy and a future human clinical study."

“该项目将开发和商业化新技术，从根本上提高X射线乳腺成像的安全性、有效性和患者舒适度。首先，该项目将调整IBEX Trueview（r）无网格散射校正方法，用于乳腺X射线摄影和数字乳腺断层合成（DBT）系统，并证明其在降低患者剂量和提高乳腺X射线摄影和DBT重建图像质量方面的有效性。初始阶段生成的体内和离体数据将用于向领先的医疗X射线系统集成商推销能力，并在项目第一年内获得商业许可交易。其次，该项目将开发并展示原型3D X射线成像系统的有效性，能够创建完整的、未压缩乳房的高对比度3D重建，患者剂量低于标准2D乳房X线摄影，且未注射造影剂。这种全新的产品有可能改变乳腺筛查和癌症诊断，特别是对于乳腺致密的女性。在第二阶段收集的离体数据将用于指导商业化策略和未来的人体临床研究。"