HIV, ETHNICITY AND ORAL DISEASE IN THE SOUTHEAST

描述：建议的项目是一个横截面和 HIV和HIV口腔表现的纵向临床研究 675名农村HIV感染者的牙周病状况 北卡罗来纳州的感染者，其中约54%将是 黑人和25%的人将是女性；两年的纵向随访是 预计将在381人中使用。校长 调查员，巴顿医生将进行标准化的面谈 问卷调查，进行口腔临床检查，并监督 从医疗记录中收集有关病史、艾滋病毒的数据 疾病分类、CD4计数和药物治疗；患者将 从同一机构的艾滋病毒诊所转诊。这项研究 将评估非法药物、酒精、烟草、性别和 种族，以及口腔中的CD4计数和疾病状态 HIV疾病的表现。假设是HIV感染者 北卡罗来纳州农村的黑人将在更大程度上 牙周病的严重性，即获得口腔健康的不同途径 护理可能在口腔疾病的发展中发挥重要作用，而且 口腔HIV感染的临床体征在最初的感染中起着关键作用 东南部黑人和女性的HIV血清学诊断。

DESCRIPTION: The proposed project is a cross-sectional and longitudinal clinical study of oral manifestations of HIV and periodontal disease status among a rural population of 675 HIV- infected persons in North Carolina, of whom approximately 54% will be blacks and 25% will be women; two year longitudinal follow-up is expected to be available in 381 persons. The principal investigator, Dr. Patton will administer a standardized interview questionnaire, conduct an oral clinical examination, and supervise collection of data from medical records on medical history, HIV disease classification, CD4 count, and medication; the patients will be referred from the HIV clinic at the same institution. The study will assess the impact of illicit drugs, alcohol, tobacco, gender, and race, as well as CD4 counts and disease status on the oral manifestations of HIV disease.The hypotheses are that HIV- infected blacks in rural North Carolina will have a greater extent and severity of periodontal disease, that differential access to oral health care may play an important role in oral disease progression, and that oral clinical signs of HIV infection play a critical role in initial serologic HIV diagnosis in blacks and females in the Southeast.