HIV, ETHNICITY AND ORAL DISEASE IN THE SOUTHEAST

产品说明： 拟议项目是一个跨部门的， 艾滋病毒口腔表现的纵向临床研究， 牙周病状况的农村人口675艾滋病毒- 北卡罗来纳州的感染者，其中约54%将是 黑人和25%将是女性; 2年纵向随访是 预计将有381人。 校长 调查员，巴顿医生将进行一次标准化的面谈 进行口腔临床检查，并监督 从病历中收集有关病史、艾滋病毒 疾病分类，CD 4计数和药物治疗;患者将 从同一机构的艾滋病毒诊所转介。 研究 将评估非法药物、酒精、烟草、性别和 种族，以及CD 4计数和口腔疾病状态 艾滋病的表现。假设是艾滋病毒感染者 北卡罗来纳州农村的黑人将有更大的程度， 牙周病严重程度、获得口腔健康的机会不同 护理可能在口腔疾病进展中起重要作用， 艾滋病毒感染的口腔临床体征在最初的 东南部黑人和女性的血清学HIV诊断。

DESCRIPTION: The proposed project is a cross-sectional and longitudinal clinical study of oral manifestations of HIV and periodontal disease status among a rural population of 675 HIV- infected persons in North Carolina, of whom approximately 54% will be blacks and 25% will be women; two year longitudinal follow-up is expected to be available in 381 persons. The principal investigator, Dr. Patton will administer a standardized interview questionnaire, conduct an oral clinical examination, and supervise collection of data from medical records on medical history, HIV disease classification, CD4 count, and medication; the patients will be referred from the HIV clinic at the same institution. The study will assess the impact of illicit drugs, alcohol, tobacco, gender, and race, as well as CD4 counts and disease status on the oral manifestations of HIV disease.The hypotheses are that HIV- infected blacks in rural North Carolina will have a greater extent and severity of periodontal disease, that differential access to oral health care may play an important role in oral disease progression, and that oral clinical signs of HIV infection play a critical role in initial serologic HIV diagnosis in blacks and females in the Southeast.