TRENDS IN DENTAL FLUOROSIS AND DENTAL CARIES

描述（改编自申请人摘要）：几项研究 表明氟斑牙患病率在过去40年中有所增加， 这一增长在非氟化地区更为明显。 氟斑牙显然与过量摄入 氟化多种来源的氟化物的贡献， 与这些风险相关的风险，已经吸引了相当大的 关注 这项研究的总体目标是确定儿童是否在 含氟和不含氟的城市都暴露在过量的 氟化物的含量增加， 氟斑牙的严重程度。 这项横断面研究将是 一系列调查中的第四个，旨在推断 随着时间的推移， 历史名城纽堡和金斯顿。 临床检查 对3,000名7至14岁的儿童进行了抽样调查， 氟化纽堡和非氟化金斯顿的1600名儿童将 进行。 关于氟斑牙的频率和严重程度的数据将 使用Dean's Index。 将进行适当的比较 评估氟中毒的发生率是增加还是减少 相比 1986年获得的数据。 龋齿趋势 还将评估纽堡和金斯顿的流行情况。 的 氟斑牙与氟斑牙的关系 被探索。这项研究将提供有关 近年来执行的建议对降低 补充剂和婴儿配方奶粉中的氟化物摄入量。 长期目标是在36岁以后进行随访检查 比较龋病发病率和检测变化 氟中毒的严重程度。

DESCRIPTION (adapted from the applicant's abstract): Several studies indicate that dental fluorosis prevalence has increased over the last 40 years and that the increase is more pronounced in non-fluoridated areas. Dental fluorosis is clearly associated with an excessive intake of fluoride. The contribution of fluoride from multiple sources, and the risks associated with these exposures, have attracted considerable attention. The overall objective of this study is to determine if children in fluoridated and non-fluoridated cities are being exposed to excessive amounts of fluoride as evidenced by an increase in the extent of severity of dental fluorosis. This cross-sectional study will be the fourth in a series of surveys intended to draw inferences about changing patterns of dental fluorosis and dental caries over time in the historical cities of Newburgh and Kingston. Clinical examinations on a sample of 3,000 seven to fourteen year old children in fluoridated Newburgh and 1600 children in non-fluoridated Kingston will be conducted. Data on frequency and severity of dental fluorosis will be collected using Dean's Index. Appropriate comparisons will be made to assess whether the occurrence of fluorosis has increased or decreased when compared to the data obtained in 1986. Trends in dental caries prevalence in Newburgh and Kingston will also be assessed. The association of fluoride tablet/drops history and dental fluorosis will be explored. This study will provide new information regarding the impact of recommendations implemented in recent years to lower fluoride intake from supplements and infant formula. The long-term objective is to conduct follow-up examinations after 36 months for comparing caries incidence rates as well as to detect changes in fluorosis severity within subjects.