Cell-Based Screening for Nutraceuticals with Anti-Osteoporotic Potential

基于细胞的抗骨质疏松保健品筛选

• 批准号: 130726
• 金额: $ 3.18万
• 依托单位: AVANTICELL SCIENCE LIMITED
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2011
• 资助国家: 英国
• 起止时间: 2011 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=130726
• 关键词: Cell; Based; Screening; Nutraceuticals; Anti

Osteoporosis is a disease affecting the quality and density of bones rendering them brittle and fragile. According to the International Osteoporosis Foundation, 200 million women worldwide are affected. The project will develop a tool, in the form of personalised cell-based analysis, for the screening of individuals pre-disposed to osteoporosis, to enable customised dietary intervention that assists prevention or supports treatment of the disease. The Study addresses directly the Competition focus on new foods with health-promoting properties, and its output creates an evidence-based means of relating genetic predeposition to osteoporosis with cellular functions that, in susceptible individuals, are directly linked to the disease's onset and aetiology.

骨质疏松症是一种影响骨骼质量和密度的疾病，使骨骼变脆和脆弱。据国际骨质疏松基金会称，全世界有2亿妇女受到影响。该项目将以个性化细胞分析的形式开发一种工具，用于筛查易患骨质疏松症的个体，以实现定制的饮食干预，帮助预防或支持疾病的治疗。该研究直接涉及竞争重点具有促进健康的特性的新食品，其产出创造了一种基于证据的方法，将遗传预沉积与骨质疏松症与细胞功能联系起来，在易感个体中，这些细胞功能与疾病的发作和病因直接相关。