Modeling the cost of a process for the manufacture of succinic acid by fermentation of syngas

对合成气发酵生产琥珀酸的工艺成本进行建模

• 批准号: 131138
• 金额: $ 2.78万
• 依托单位: ZUVASYNTHA LIMITED
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=131138
• 关键词: Modeling; cost; process; manufacture; succinic

This project will develop a model of the process economics of BioSyntha's novel technology for synthesis of platform chemicals by fermentation of syngas made from lignocellulosic biomass. The model will underpin Biosyntha's business plan to maximise and extract value from its R&D. Syngas fermentation is in its infancy in the world and there is no readily available model for syngas fermentation processes. This project will assist in the development of this technology into full commercial production by aligning process parameters such as target product yields and production rates, with metabolic engineering objectives. Economic validation of the principle of converting syngas derived from multiple and flexible sources to platform chemicals by a fermentative approach, and comparison with alternate routes, will allow the company to attract further investment and to develop collaborative relationships with industrial partners.

该项目将开发BioSyntha新技术的过程经济学模型，该技术通过发酵由木质纤维素生物质制成的合成气合成平台化学品。该模式将支持Biosyntha的商业计划，使其研发价值最大化并从中提取价值。合成气发酵在世界上还处于起步阶段，目前还没有现成的合成气发酵过程模型。该项目将通过调整工艺参数，如目标产品产量和生产率，与代谢工程目标相一致，帮助该技术发展到完全商业化生产。通过发酵方法将多种灵活来源的合成气转化为平台化学品的原理进行经济验证，并与替代路线进行比较，将使公司能够吸引进一步的投资，并与工业伙伴建立合作关系。