Tunable Laser Source for Confocal Microscopy

用于共焦显微镜的可调谐激光源

• 批准号: 131683
• 金额: $ 3.04万
• 依托单位: M-SQUARED LASERS LIMITED
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=131683
• 关键词: Tunable; Laser; Source; Confocal; Microscopy

Confocal microscopy is one of the most widely used techniques in biosciences. High resolution images are produced through laser excitation of fluorescent molecules in the blue-green region of the spectrum. Lasers provide light at only a few fixed wavelengths and this limits the brightness of the image. M Squared proposes to overcome this limitation by developing a continuously tuneable laser source covering the whole region of relevance to confocal microscopy. The project will deliver a demonstrator using a novel approach. Given the size of the market, the potential return on investment over 10 years is well in excess of 100 times. M Squared is an early stage business whose growth is highly reliant on technological development and innovation. Funding from the TSB is essential to offset the risks of undertaking this ambitious research project.

共聚焦显微镜是生物科学中应用最广泛的技术之一。高分辨率的图像是通过激光激发光谱蓝绿区域的荧光分子产生的。激光只提供几个固定波长的光，这限制了图像的亮度。M Squared提出通过开发一种连续可调谐的激光源来克服这一限制，该激光源覆盖了与共聚焦显微镜相关的整个区域。该项目将使用一种新颖的方法进行演示。考虑到市场的规模，未来10年的潜在投资回报率远远超过100倍。M Squared是一家早期企业，其增长高度依赖于技术开发和创新。来自TSB的资金对于抵消承担这一雄心勃勃的研究项目的风险至关重要。