NEUROMAGNETIC MAPPING OF MULTIPLE VISUAL AREAS IN HUMANS

这项建议旨在识别和表征多个视觉 通过使用神经磁学测量人类大脑的区域，在 与磁共振成像技术相结合。虽然之前 非侵入性研究表明人类存在原始视网膜移植的证据 大脑，目前还缺乏对这种视网膜移植的更全面的描述。那里 还没有系统地研究过 视野表示也不是这些的具体功能 区域。这里提出的实验使用的是瞬时诱发反应 技术将分两个阶段进行：1)视网膜原位标测和 2)视觉区域的功能表征。 视网膜标测将通过标测神经磁场进行 小圆形正弦(靶)刺激引起的分布 与垂直方向和垂直方向平行的不同偏心率 水平子午线和视野中的45度对角线。 视觉区域的功能表征将重点放在 颜色，因为此参数已成功区分 非人灵长类动物的视觉区域。颜色对比度和亮度 正弦光栅将被操纵，以便优先 激活颜色/表格系统。 该项目的长期目标是勾勒出具体的 人脑中的信息处理路径。功能界别 对不同视觉区域的表征最终将有助于 更好地理解高级认知功能。

This proposal is aimed at identifying and characterizing multiple visual areas in the human brain through the use of neuromagnetic measurements, in conjunction with magnetic resonance imaging techniques. Although previous noninvasive studies have shown evidence of crude retinotopy in the human brain, a more thorough description of this retinotopy is lacking. There have been no studies which have systematically examined the arrangement of the visual field representations nor the specific functions of these areas. The experiments proposed here, using transient evoked response techniques, will be carried out in two phases: 1) retinotopic mapping and 2) functional characterization of visual areas. Retinotopic mapping will be performed by mapping neuromagnetic field distributions evoked by small circular sinusoid (Target) stimuli of differing eccentricity presented in parallel with the vertical and horizontal meridians and on 45 degree diagonals in the visual field. Functional characterization of visual areas will focus on manipulations of color since this parameter has been successful in differentiating between visual areas in nonhuman primates. The chromatic contrast and luminance of sinusoidal gratings will be manipulated in order to preferentially activate the color/form system. The long-term goal of the project is the delineation of specific information processing pathways in the human brain. The functional characterization of the different visual areas will ultimately aid in a better understanding of higher cognitive functions.