Meta-microscopy of insect tissue: How nature grows bicontinuous nanosolids

昆虫组织的元显微镜：大自然如何生长双连续纳米固体

• 批准号: DP200102593
• 负责人: Prof Gerd Schroeder-Turk
• 金额: $ 25.83万
• 依托单位: Murdoch University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200102593
• 关键词: Meta; microscopy; insect; tissue; How

Several butterfly species grow a complex nano-sculptured matrix whose chiral network structure confers remarkable optical properties, including jewel-like reflections. The formation process remains mysterious and a spectacular case of bottom-up self-assembly at far larger scales than accessible in the lab. The project aims to decipher this process, by (a) tomography of a species where arrested growth sites represent time-frozen snapshots of the development, and (b) by a combination of micron-resolved in-vivo microscopy of a developing butterfly wing with a growth model to infer nanometer-scale information. This insight will lead to blueprints for self-assembly strategies and shed light on function and form of inner-cellular membranes.

几种蝴蝶生长出复杂的纳米雕刻矩阵，其手性网络结构赋予显着的光学特性，包括宝石般的反射。形成过程仍然是神秘的，是一个壮观的自下而上的自组装案例，其规模远大于实验室中的规模。该项目旨在通过以下方式破译这一过程：（a）对一个物种进行断层扫描，其中生长停滞的部位代表发育的时间冻结快照;（B）将发育中的蝴蝶翅膀的微米分辨率活体显微镜与生长模型相结合，以推断纳米级信息。这一见解将导致自组装策略的蓝图，并阐明细胞内膜的功能和形式。