DEVELOPMENTAL BIOLOGY AND GENETICS OF THE MAIZE LEAF

叶是重复茎段中最明显的部分， 植物单子叶植物的叶子分为两部分： 底部和从植物中伸出的叶片。 我们的数据支持 叶子实际上是基因域拼凑的概念。 在 叶鞘-叶片边界为舌区。 在玉米中， 20个不同基因中的突变等位基因，改变了所有或部分的 刀鞘边界 其中五个是克隆的，还有几个是 我们可以描述它们的功能。 一些编码同源结构域蛋白质的类型是已知的特别是 动物发育的重要转录调节因子。总的来说， 我们的目标是将这些基因的功能整合到一个系统中， 场、域、诱导、转导和反应， “位置信息”和“发展时间表”的概念 可能会有所区别。 也许我们工作中最独特的方面是我们能够 在遗传上扰乱了各种发育的计时功能。 我们可以 获得异时性变化的分子机制， 在动物系统中很难做到。 我们提出了一种抑制屏， 获得特异性加速发育或转化的突变体 植物的幼年部分变得更成熟。 我们已经开始减少 异时理论，流行的概念，涉及进化， 发展，分子机制。

The leaf is the most visible part of the repeating shoot segment in plants. Monocotyledonous plants have leaves in two parts: the sheath at the base and the blade that extends out from the plant. Our data supports the concept that the leaf is actually a patchwork of gene domains. At the sheath-blade boundary is the ligular region. In maize, we have many mutant alleles in 20 different genes that alter all or a portion of the blade-sheath boundary. Five of these are cloned and several more are characterized to the level that we can say something about their function. Some encode homeodomain proteins of the type known to be particularly important transcriptional regulators of animal development. In general, our aim is to integrate the function of these genes into a system of fields, domains, inductions, transductions and responses where the related concepts of "positional information" and "developmental time schedules" might be distinguished. Perhaps the most unique aspect of our work is the way we are able to genetically perturb various developmental time-keeping functions. We can obtain molecular mechanisms for heterochronic shifts that would be very difficult to do in animal systems. We propose a suppressor screen to obtain mutants that specifically accelerate development or transform juvenile parts of the plant to be more adult. We have begun to reduce heterochronic theory, the prevailing concepts that relate evolution to development, to molecular mechanisms.