Enhancing biopharmaceuticals: A disruptive bioseparation resin technology

增强生物制药：颠覆性生物分离树脂技术

• 批准号: DP200100874
• 负责人: Prof Bernd Rehm
• 金额: $ 35.81万
• 依托单位: Griffith University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-03-20 至 2024-03-19
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200100874
• 关键词: Enhancing; biopharmaceuticals; disruptive; bioseparation; resin

This project aims to develop an innovative and disruptive platform technology for designing and manufacturing tailor-made high-performance bioseparation resins to enhance biopharmaceuticals manufacturing. Bacterial cell factories will be developed to enable biotechnological production of innovative polyester bead-based bioseparation resins, which will revolutionise manufacturing of biopharmaceuticals. Expected outcomes of this project are cost-effective and strongly enhanced approaches for biopharmaceuticals recovery, thereby providing significant benefits to accelerate research and development in early stage discovery and manufacture of biologics, therapeutic proteins and vaccines.

该项目旨在开发一种创新和颠覆性的平台技术，用于设计和制造量身定制的高性能生物分离树脂，以增强生物制药制造。将开发细菌细胞工厂，以实现创新聚酯珠基生物分离树脂的生物技术生产，这将彻底改变生物制药的制造。这一项目的预期成果是具有成本效益和强有力地加强生物制药回收的方法，从而为加快早期发现和生产生物制剂、治疗性蛋白质和疫苗的研究和开发提供重大好处。