Metal-free strategies for sustainable light-driven synthesis

可持续光驱动合成的无金属策略

• 批准号: DE200100949
• 负责人: Dr Daniel Priebbenow
• 金额: $ 29.87万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-13 至 2024-01-12
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE200100949
• 关键词: Metal; free; strategies; sustainable; light

Innovation in synthetic chemistry drives the discovery of new life-saving drugs, agrochemicals and functional materials. This project aims to use visible light to access underexploited reactive intermediates and harness their unique reactivity in new sustainable synthetic transformations. The new chemical processes are expected to deliver increased economy, efficiency and precision in the synthesis of bioactive molecules that are inaccessible or challenging to prepare with existing technologies. The conceptual and practical outcomes of this project are expected to benefit both academia and industry as the use of hazardous and expensive metal catalysts can be avoided, reducing chemical waste and simplifying purification.

合成化学的创新推动了新的救生药物、农用化学品和功能材料的发现。该项目旨在利用可见光来获取未充分开发的活性中间体，并在新的可持续合成转化中利用其独特的反应性。新的化学工艺有望提高生物活性分子合成的经济性、效率和精度，而这些生物活性分子是现有技术无法获得或难以制备的。该项目的概念和实际成果预计将使学术界和工业界受益，因为可以避免使用危险和昂贵的金属催化剂，减少化学废物并简化净化。