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REGULATION OF GABA-A RECEPTOR SUBUNIT EXPRESSION

REGULATION OF GABA-A RECEPTOR SUBUNIT EXPRESSION
GABA-A 受体亚基表达的调控
批准号:
2259657
负责人:
DENNIS R GRAYSON
金额:
$6.45万
依托单位国家:
美国
项目类别:
财政年份:
1993
资助国家:
美国
项目状态:
已结题
起止时间:
1993-09-01 至 1998-08-31

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中文摘要
翻译
在研究计划的背景下,竞争性PCR分析将是
英文摘要
In the context of the research proposal, a competitive PCR assay will be used to analyze the profiles of expression of the mRNAs encoding subunits of the GABA-A receptor during development (in vivo) and as cerebellar granule cells differentiate in vitro. This information will be correlated with a comparable in situ hybridization analysis during development in vivo. The hypothesis that cell type specific patterns of expression of the receptor subunit mRNAs are influenced by both heterologous and homologous receptor stimulation will be tested. In the context of, the mechanism by which this trans-synaptic regulation of GABA-A receptor subunit mRNAs occurs will be investigated.
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Epigenetics Core
  • 批准号:
    10613948
  • 项目类别:
  • 资助金额:
    $26.65万
  • 财政年份:
    2015
  • 负责人:
    DENNIS R GRAYSON
  • 依托单位:
Epigenetics Core
  • 批准号:
    10380647
  • 项目类别:
  • 资助金额:
    $26.71万
  • 财政年份:
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  • 负责人:
    DENNIS R GRAYSON
  • 依托单位:
Regulation of the Reelin Gene
  • 批准号:
    6719046
  • 项目类别:
  • 资助金额:
    $27.28万
  • 财政年份:
    2002
  • 负责人:
    DENNIS R GRAYSON
  • 依托单位:
Regulation of the Reelin Gene
  • 批准号:
    6481449
  • 项目类别:
  • 资助金额:
    $31.17万
  • 财政年份:
    2002
  • 负责人:
    DENNIS R GRAYSON
  • 依托单位:
海外基金