The development of a new, highly-efficacious, 100% natural, anti-viral active ingredient

%20开发%20%20a%20新、%20高效、%20100%%20天然、%20抗病毒%20活性%20成分

• 批准号: 47612
• 金额: $ 44.35万
• 依托单位: BYOTROL TECHNOLOGY LIMITED
• 依托单位国家: 英国
• 项目类别: Study
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=47612
• 关键词: development; new; highly; efficacious; 100

Despite rapid advances in healthcare and medical technology, viruses continue to pose a major threat to human, animal and plant health, costing economies hundreds of billions each year. Easily transmitted and immune to antibiotics, viruses (particularly non-enveloped) such as Norovirus, Polio virus and Adenovirus are very difficult to eradicate and even more expensive to treat through a limited number of antiviral solutions (£53.9bn global spend by 2025 [Grandview Research][0]). Norovirus alone kills 219k people per annum and sickens nearly 700m globally, costing £44bn per year in healthcare and lost productivity (£115m NHS cost pa) ([Telegraph][1]). Furthermore, they are becoming increasingly resistant to the current antiviral agents.Leading state of the art antiviral solutions on the market are either based upon bleach (5% active, synthetic, corrosives, hazardous to touch) or ethanol (c60% active, synthesised, requires high concentration, short-lasting benefit, dries skin out).Working in close partnership with the Department of Virology at Manchester University and based upon 4 years of research, we intend to explore and harness the highly efficacious properties of seaweed as a new, 100% natural, sustainable antiviral active ingredient for cleaning products (medium term) and medicines (long term).[0]: https://www.grandviewresearch.com/press-release/global-antiviral-drugs-market[1]: https://www.telegraph.co.uk/news/2016/04/26/norovirus-costs-the-world-some-44-billion-per-year-says-new-stud/

尽管医疗保健和医疗技术迅速发展，但病毒仍然对人类、动物和植物健康构成重大威胁，每年造成数千亿美元的经济损失。诺如病毒、脊髓灰质炎病毒和腺病毒等病毒（特别是无包膜病毒）易于传播且对抗生素具有免疫力，因此很难根除，通过数量有限的抗病毒解决方案进行治疗的成本甚至更高（到2025年全球支出为539亿英镑[Grandview Research][0]）。仅诺如病毒每年就导致21.9万人死亡，全球近7亿人患病，每年在医疗保健和生产力损失方面花费440亿英镑（NHS成本为1.15亿英镑）。此外，它们对目前的抗病毒药物的耐药性越来越强。市场上最先进的抗病毒溶液要么是基于漂白剂，（5%活性，合成，腐蚀性，接触有害）或乙醇（c 60%活性，合成，需要高浓度，短期持续效益，皮肤干燥）。与曼彻斯特大学病毒学系密切合作，并基于4年的研究，我们打算探索和利用海藻的高效特性，将其作为一种新的、100%天然的、可持续的抗病毒活性成分，用于清洁产品（中期）和药物（长期）。[0]：https：//www.grandviewresearch.com/press-release/global-antiviral-drugs-market [1]：https://www.telegraph.co.uk/news/2016/04/26/norovirus-costs-the-world-some-44-billion-per-year-says-new-stud/