Orientated biointerfacing of cell-mimetic nanoparticles

细胞模拟纳米粒子的定向生物界面

• 批准号: DP240100770
• 负责人: A/Prof Zi (Sophia) Gu
• 金额: $ 39.37万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP240100770
• 关键词: Orientated; biointerfacing; cell; mimetic; nanoparticles

The project aims to create next-generation cell-mimetic nanotechnology by providing in-depth understandings and precise control over cell membrane coating orientation of biomimetic nanoparticles. Our approach is to design and develop new synthetic and analytic strategies to construct and quantify orientated biointerfacing. This will generate new knowledge and patentable methodologies related to orientated biomimetic nanoparticles. Expected outcomes include significant contributions to Australia's scholarly outputs, enhanced national capacity in disruptive nanotechnology, new opportunities for national value-add material manufacturing, and long-term benefits to biomedical and veterinary industries through new materials and nanotechnologies.

该项目旨在通过提供对仿生纳米颗粒的细胞膜涂层取向的深入理解和精确控制来创建下一代细胞模拟纳米技术。我们的方法是设计和开发新的合成和分析策略，以构建和量化定向生物界面。这将产生与定向仿生纳米颗粒相关的新知识和可专利的方法。预期成果包括对澳大利亚的学术产出作出重大贡献，提高国家在破坏性纳米技术方面的能力，为国家增值材料制造提供新的机会，以及通过新材料和纳米技术为生物医学和兽医行业带来长期利益。