Order from chaos: Rational design of biointerfacing plasma polymer coatings

混沌中的秩序：生物界面等离子体聚合物涂层的合理设计

• 批准号: DP160105001
• 负责人: Prof Hans Griesser
• 金额: $ 18.22万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-09-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP160105001
• 关键词: Order; chaos; Rational; design; biointerfacing

The project goal is to facilitate a new generation of bio-interface platforms to be designed using plasma processing. Functionalised plasma polymer surfaces used for bio-interfaces result from random processes in the plasma phase and at the surface. While rules-of-thumb exist for tailoring simple functionalised plasma polymers, detailed knowledge linking plasma processes to surface chemistry is lacking. Using a homologous series of precursors, the project aims to unravel physical and chemical plasma processes to enable retention of complex surface functional groups which are critical for subsequent surface processing. This is designed to be achieved by linking plasma physics and chemistry via plasma phase mass spectrometry and surface analysis.

该项目的目标是促进新一代的生物界面平台设计使用等离子体处理。用于生物界面的官能化等离子体聚合物表面由等离子体相中和表面处的随机过程产生。虽然存在用于定制简单功能化等离子体聚合物的经验法则，但缺乏将等离子体工艺与表面化学联系起来的详细知识。该项目使用一系列同源前体，旨在揭示物理和化学等离子体工艺，以保留对后续表面处理至关重要的复杂表面官能团。这被设计为通过等离子体相质谱和表面分析将等离子体物理和化学联系起来来实现。