NOVEL THROMBOLYTIC ENZYMES

新型溶栓酶

• 批准号: 2222572
• 负责人: RONALD A BUTOW
• 金额: $ 25.14万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-09-30 至 1995-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2222572
• 关键词: anticoagulants; antifibrinolytic agents; disease /disorder model; enzyme biosynthesis; enzyme mechanism; fibrinolysis; fibrinolytic therapy; model design /development; mutant; myocardial infarction; plasminogen activator; radiotracer; site directed mutagenesis; zymogens

项目成果

Blockade of platelet membrane glycoprotein Ib receptors delays intracoronary thrombogenesis, enhances thrombolysis, and delays coronary artery reocclusion in dogs.

阻断血小板膜糖蛋白 Ib 受体可延迟狗冠状动脉内血栓形成、增强血栓溶解并延迟冠状动脉再闭塞。

• DOI: 10.1161/01.cir.89.6.2822
• 发表时间: 1994
• 期刊: Circulation
• 影响因子: 37.8
• 作者: Yao,SK;Ober,JC;Garfinkel,LI;Hagay,Y;Ezov,N;Ferguson,JJ;Anderson,HV;Panet,A;Gorecki,M;Buja,LM
• 通讯作者: Buja,LM