HIP BONE DENSITY IN ELDERLY AFRICAN AMERICAN WOMEN

非洲裔美国老年女性的髋骨密度

• 批准号: 3738888
• 负责人: ARLINE D BOHANNON
• 金额: --
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3738888
• 关键词: African American; alleles; bone density; bone metabolism; disease /disorder proneness /risk; female; gene frequency; hip; hip fractures; homeostasis; human old age (65+); human subject; prognosis; racial /ethnic difference; vitamin D

The purpose of this study is to identify any racial differences in bone mineral density, bone mineral homeostasis and bone turnover among community- dwelling elderly women (ages 70-80). Racial differences in vitamin D receptor allele frequencies will also be determined. It is anticipated that after thorough characterization of bone metabolism in elderly African American women, inferences can be drawn concerning predictors for their hip fracture risk.

本研究的目的是确定骨骼方面的种族差异 矿物质密度、骨矿物质稳态和骨转换 居住在社区的老年妇女（70-80 岁）。 种族差异 维生素 D 受体等位基因频率也将被确定。 这是 预计在对骨代谢进行彻底表征后 老年非洲裔美国妇女，可以得出以下推论 髋部骨折风险的预测因素。