DIGITAL RECORDER FOR ACQUIRING ELECTROPHYSIOLOGY SIGNALS

用于采集电生理信号的数字记录仪

• 批准号: 2272811
• 负责人: RICHARD E RENCK
• 金额: $ 9.93万
• 依托单位: R.C. ELECTRONICS, INC.
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-05-15 至 1996-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2272811
• 关键词: biomedical equipment development; computer data analysis; electrodes; electrophysiology; method development; neural information processing; personal computers

Investigating individual neurons has proven very useful in understanding their functionality. However, all biological systems are composed of a multitude of neurons that interact with a variety of sensory and skeletal muscular systems. Researchers are anxious to have the ability to record a large number of neuron firing patterns to study how they communicate and interact in a biological system. Tools such as the multi-channel electrode have been created to study the interactions of large numbers of neurons. However, in order to record all the channels, the researcher must gang several recorders together. This leads to difficulties in accurately matching all the channels during playback, because of the complexity of ganged multiple recorders. R.C . Electronics Inc. proposes to build a low cost, high speed digital recorder utilizing PC technology. This digital recorder will be able to record continuously to a mass storage device at an aggregate rate of 1 MHz. It will also provide the researcher with the ability to acquire up to 96 channels, with each channel sampled at 10 KHz; higher speeds will be possible with fewer channels. PROPOSED COMMERCIAL APPLICATION: There is a market demand for the digital recorder in the multitude of life science applications engaged in complex biological system studies (please review Significance, page 7). We also believe that this will be a good industrial recorder, capable of replacing the existing analog and DAT recorders for acoustic, noise, and vibration studies. There will also be a market to replace some of the high-end work stations based on HP, Concurrent, and Sun data acquisition systems.

研究单个神经元已被证明对于理解非常有用 他们的功能。 然而，所有的生物系统都是由 大量的神经元与各种感觉和相互作用相互作用 骨骼肌肉系统。 研究人员渴望拥有这样的能力 记录大量神经元放电模式以研究它们如何 在生物系统中进行交流和相互作用。 工具如 创建多通道电极来研究相互作用 大量的神经元。 然而，为了记录所有频道， 研究人员必须将多个记录器组合在一起。 这导致 播放时难以准确匹配所有频道， 由于组合多个记录器的复杂性。 RC. Electronics Inc. 提议构建低成本、高速数字 利用PC技术的录音机。 该数字录音机将能够 以总速率连续记录到大容量存储设备 1兆赫。 它还将为研究人员提供获取 多达 96 个通道，每个通道采样频率为 10 KHz；更高的速度 用更少的渠道就可以实现。 拟议的商业应用：有市场需求 数字记录仪在众多生命科学应用中的应用 在复杂的生物系统研究中（请查看重要性，页面 7). 我们也相信这将是一款优秀的工业记录仪， 能够取代现有的模拟和 DAT 录音机用于声学、 噪声和振动研究。 也会有市场来替代 一些基于 HP、Concurrent 和 Sun 数据的高端工作站 采集系统。