CENTRALIZING NEUROSCIENCE RESEARCH ANIMAL RESOURCES

集中神经科学研究动物资源

• 批准号: 3059284
• 负责人: JOSEPH S SPINELLI
• 金额: $ 47.59万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-09-30 至 1993-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3059284
• 关键词: animal care; biomedical facility; building /facility design /renovation

The general objective of this project is to upgrade the University of California at San Francisco (UCSF) animal resource. UCSF has short term and long term goals to improve animal care or services to faculty. This project fits in with both. The project will provide an animal resource for laboratories that conduct neuroscience research, which has been identified by the Dean of the School of Medicine as one of three major areas for development at UCSF in the next five years. These scientists conduct basic research to understand how groups of brain cells work together to generate behavior. They have developed animal models for studying phenomena such as pain, vision, learning and memory, somatic sensation, and sensory control of movement. They conduct experiments on mammals whose brains are organized like the human brain. Species include monkeys, cats, ferrets, and rats. The project will renovate and equip animal holding rooms and a surgical suite that can be used for aseptic survival procedures. This will improve the care of the animals by placing them near the laboratories and offices of the researchers who use them, reducing their contact with potentially infectious agents by eliminating the current need to move them large distances through public corridors, and improving their psychological well- being by providing improved caging and by reducing the number of strangers they encounter. The new surgical suite is required so that neuroscience faculty can conduct some research that is currently not possible and so that they can be ensured access to a facility that is appropriate for their survival surgery procedures. Survival surgery is a critical element of research in integrative neuroscience. The new surgery will provide an optimal facility in which neuroscience faculty will have the first priority to conduct survival procedures under procedures under optimal conditions.

该项目的总体目标是升级大学 加州旧金山 (UCSF) 动物资源。 UCSF有短期 以及改善动物护理或教师服务的长期目标。 这 项目适合两者。 该项目将为 进行神经科学研究的实验室已被确定 被医学院院长列为三大领域之一 UCSF未来五年的发展。 这些科学家进行了基础研究 研究了解脑细胞群如何协同工作以产生 行为。 他们开发了动物模型来研究诸如 疼痛、视觉、学习和记忆、躯体感觉和感觉控制 的运动。 他们对大脑有缺陷的哺乳动物进行了实验 像人脑一样组织。 物种包括猴子、猫、雪貂、 和老鼠。 该项目将翻新和装备动物饲养室和手术室 可用于无菌生存程序的套件。 这会改善 将动物放置在实验室和办公室附近来照顾它们 使用它们的研究人员，减少他们与潜在的接触 通过消除当前将传染源大规模移动的需要 通过公共走廊的距离，并改善他们的心理健康 通过提供改进的笼子和减少陌生人的数量 他们相遇。 需要新的手术室，以便神经科学教师可以进行 一些目前不可能的研究，以便它们可以 确保能够使用适合其生存手术的设施 程序。 生存手术是研究的一个关键要素 综合神经科学。 新手术将提供最佳设施 其中神经科学教师将优先进行 最佳条件下的生存程序。