Programming Polymer Function via Ring-opening Polymerisation of Peptides

通过肽的开环聚合来编程聚合物功能

• 批准号: DE200101096
• 负责人: A/Prof Hendrik Frisch
• 金额: $ 29.99万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-02-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE200101096
• 关键词: Programming; Polymer; Function; via; Ring

The project aims to set the foundation of a class of intelligent polymers, whose structure and function – including catalytic activity and biodegradability – can be readily programmed. In contrast to well-established radical polymerization techniques leading to all-carbon based backbones, the outlined research will develop technologies to incorporate short peptides into the backbones of synthetic polymers. The synthetically adjustable amino acid sequence of the main chain embedded peptides will translate into the structure and function of the modular polymer. The DECRA will deliver unprecedented access towards tailor-made mechanical properties, catalytic activity and biodegradability of polymeric materials.

该项目旨在为一类智能聚合物奠定基础，其结构和功能-包括催化活性和生物降解性-可以很容易地编程。与成熟的自由基聚合技术导致全碳基主链相反，概述的研究将开发将短肽纳入合成聚合物主链的技术。主链嵌入肽的可合成调节的氨基酸序列将转化为模块聚合物的结构和功能。DECRA将为聚合物材料提供前所未有的定制机械性能，催化活性和生物降解性。