A nanodiamond voltage sensor: towards real-time, long-term neuronal sensing

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This project aims to develop a voltage sensor that may ultimately be used to measure neuronal signals noninvasively in real-time and over hours. The project expects to generate the fundamental science needed to use nanodiamonds for fluorescence-based voltage sensing that can be easily measured using optical microscopy. The expected outcome is a biocompatible sensor that should provide a solution to one of the biggest challenges in neuroscience; the fast, precise and long-term measurement of neuronal activity. This technology may one day inform our understanding of how the normal brain works and provide major insights into mental health conditions and neurodegenerative diseases.