STRUCTURE/FUNCTION ANALYSIS OF YEAST MITOCHONDRIAL HSP70

对分子伴侣的功能有更好的认识 介导蛋白质折叠具有基本的生物学意义，但可能 也有助于更好地了解某些疾病，如癌症。 吉姆·罗斯曼的部门在分子伴侣领域处于领先地位 和催化蛋白质折叠(见申请)，因此是理想的 在这方面进行培训的地方。我相信做后处理- 在这个杰出的实验室里做博士工作是一个独特的学习机会 结构-功能研究的最新技术和方法 包括伴侣、细胞生物学和蛋白质化学，这将是非常重要的 对我的研究生涯很有价值。

A better understanding of the function of molecular chaperones in mediating protein folding is of fundamental biological interest, but may also contribute to better understanding of some diseases such as cancer. Jim Rothman's department is leading in the field of molecular chaperones and catalyzed protein folding (see application), and is thus the ideal place for training in this area. It is my belief that doing post- doctoral work in this outstanding laboratory is a unique chance to learn state of the art techniques and approaches in structure-function studies of chaperones, cell biology, and protein chemistry, which will be highly valuable for my research career.