FASEB RESEARCH CONFERENCE: TRANSCRIPTION REGULATION

通过转录进行基因调节是人类共同的基本过程 所有的生物系统。转录调控是关键的 细胞行为方面，包括增殖和分化， 很可能在开发过程中推动关键事件。基因缺陷 监管与各种人类疾病有关，包括 癌该申请要求资助夏季FASEB会议， 分化、发育和疾病的转录调控。 这次会议的目的是汇集研究人员从事 使用不同的方法研究广泛的转录过程， 方法和生物系统。目标是提供一个深入的 鉴于这一迅速扩大的领域，使方法和概念 具体领域的进展可以迅速传播，并应用于新的 问题和制度。每次会议分组讨论， 专注于转录研究关键领域的不同方法。的 会议旨在提供最新进展的概述， 从蛋白质结构和基本机制的基础和激活 转录到组织特异性转录、发育和致癌 转录因子会议将强调 转录调节在正常分化中起作用， 发育和异常基因表达参与的方式 在癌症和其他疾病的发生中起着重要作用。转录控制 脊椎动物胚胎发生，肌肉和血液的发育， 将特别强调激素调节。 会议将在加州大学圣克鲁斯分校举行 1994年8月14日至19日，校园。会议将包括正式会谈， 非正式海报会议、讨论时间和充分的机会， 与会科学家之间的互动。与会者将包括 主要研究者、博士后研究员和研究生。的 会议将提供一个最新的和具有成本效益的概述 生物学中最基本和最迅速发展的领域， 期望为进一步的研究提供新的思路和策略。

Gene regulation through transcription is a fundamental process common to all biological systems. Transcriptional regulation underlies critical aspects of cell behavior including proliferation and differentiation and is likely to drive key events during development. Defects in gene regulation have been linked to a wide variety of human diseases including cancer. This application requests funding for a summer FASEB conference on Transcriptional Regulation of Differentiation, Development and Disease. The intent of this conference is to bring together researchers engaged in studying a broad range of transcriptional processes using different methodologies and biological systems. The goal is to provide an in-depth view of this rapidly expanding field so that methodological and conceptual advances in specific areas can be rapidly disseminated and applied to new problems and systems. Each conference session groups together talks that focus on different approaches to key areas of transcription research. The sessions are designed to provide an overview of recent advances ranging from protein structure and fundamental mechanisms of basal and activated transcription to tissue specific transcription, development, and oncogenic transcription factors. The conference will underscore the important role that transcription regulation plays in normal differentiation and development and the manner in which aberrant gene expression in involved in the genesis of cancer and other diseases. Transcription control in vertebrate embryogenesis, in the development of muscle and blood, and in hormonal regulation will be particularly emphasized. The conference will be held at the University of California Santa Cruz campus from August 14-19 1994. The meeting will include formal talks, informal poster sessions, discussion periods and ample opportunity for interaction among the attending scientists. Attendees will include principal investigators, postdoctoral fellows and graduate students. The conference will provide an up-to-date and cost-effective overview of one of the most fundamental and rapidly moving fields in biology and is expected to generate new ideas and stratagems for further research.