CONFERENCE ON BREAST AND PROSTATE CANCER

乳腺癌和前列腺癌会议

• 批准号: 2104448
• 负责人: MARC E LIPPMAN
• 金额: $ 0.5万
• 依托单位: KEYSTONE CENTER
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-02-01 至 1995-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2104448
• 关键词: breast neoplasms; meeting /conference /symposium; prostate neoplasms; travel

Breast and prostate cancers are two of the three diseases recently designated as high priority targets of the SPORE funding mechanisms. This conference includes researchers from each of these designated SPORE centers; along with many other current investigators, to promote maximal interaction and exchange. This is a unique meeting dedicated to a comparative, multidisciplinary approach in uncovering mechanisms at work in two of the deadliest cancers of men and women. Cancers of the mammary and prostate glands are uniquely linked in their dependence upon sex steroid hormones for onset and malignant progression. Recent studies have also begun to explore potential commonalities in mechanisms of familial pre-disposition, mutations of respective sex steroid receptors, oncogenes, and suppressor genes, mechanisms of local control by growth factors and mechanisms of metastatic spread to distant sites. The meeting will highlight dialogue in these areas with a goal of improved diagnosis and movement toward new chemo-,hormonal and biological therapies of the two diseases. Sessions will be designed to cross fertilize ideas in topics ranging from basic cell and molecular biology to new clinical trials based on new understanding of breast and prostate tumor biology and utilization of new therapeutic agents.

乳腺癌和前列腺癌是近期三大疾病中的两种 被指定为 SPORE 资助机制的高度优先目标。 这 会议包括来自这些指定 SPORE 的研究人员 中心；与许多其他当前的研究人员一起，以促进最大限度 互动与交流。 这是一次独特的会议，致力于 比较、多学科方法揭示工作机制 男性和女性两种最致命的癌症。 乳腺癌 前列腺对性的依赖有着独特的联系 类固醇激素用于发病和恶性进展。 最近的研究有 也开始探索家族机制中潜在的共性 易感性、各自性类固醇受体的突变、癌基因、 和抑制基因，生长因子的局部控制机制和 转移扩散到远处部位的机制。 会议将 强调这些领域的对话，以改善诊断和 两者的新化学、激素和生物疗法的发展 疾病。 会议旨在交流主题中的想法 范围从基础细胞和分子生物学到基于新的临床试验 对乳腺和前列腺肿瘤生物学和利用的新认识 新的治疗剂。