SYNTHESIS OF CONGENERS & PRODRUGS OF ANTI-AIDS COMPOUNDS

同系物的合成

• 批准号: 3615897
• 负责人: DAVID C BAKER
• 金额: $ 14.59万
• 依托单位: UNIVERSITY OF ALABAMA IN TUSCALOOSA
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-05-31 至 1991-05-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3615897
• 关键词: AIDS; antiAIDS agent; drug design /synthesis /production; prodrugs

The specific objectives of this project are: (a) to synthesize congeners of synthetic compounds with confirmed activity; (b) to design and synthesize prodrugs and other compounds that possess elements of both congener and prodrug; (c) to synthesize compounds related to products of natural origin and other related heterocycles; and (d) to synthesize anti-sense nucleic acids.

该项目的具体目标是：(A)合成 具有确定活性的合成化合物；(B)设计和合成 前体药物和其他同时具有同种元素和 前体药物；(C)合成与天然产物有关的化合物 以及(D)合成反义核酸 酸。