CORONARY HEART DISEASE AND STROKE IN PEOPLE AGED 65-84

本研究的主要目的是调查危险因素 老年人冠心病和中风 65-84）。 在中年人群中确定的两种风险因素 并对疑似危险因素进行检查。 由于动脉粥样硬化 在老年人中普遍存在，研究将集中在认为 诱发临床上明显的疾病 它将以两种方式这样做：1）它 将从以下指标评估临床疾病的预测 临床前疾病，如颈动脉粥样硬化，左 心室损害和心律失常或 心肌缺血 2)由于心血管事件可能发生 在老年人中，由于健康或生活环境， 在事件发生前的几个月内可能发生了变化， 我会经常联系参与者， 并发疾病状况、社会支持 网络，紧张的生活状况，饮食，体育活动和 其他风险因素。 这项研究有三个与老年人有关的次要目标 （1）评价与之相关的因素 临床前心血管疾病（如颈动脉 动脉粥样硬化、左心室损害和 心律失常或心肌缺血）; 2）评估 残疾、住院和死亡率， 患有冠心病或中风; 3）测量利用率和影响 冠心病和中风的医疗保健服务。 承包商应作为本研究的现场中心。 的 现场中心的职责包括招聘适当的 队列，进行访谈和临床检查，监测 和数据分析。

The primary objective of this study is to investigate risk factors for coronary heart disease (CHD) and stroke in the elderly (aged 65-84). Both risk factors established in middle-aged populations and suspected risk factors will be examined. Since atherosclerosis is prevalent in the elderly, the study will focus on factors thought to induce clinically overt disease. It will do so in two ways: 1) It will assess the prediction of clinical disease from measures of preclinical disease, such as carotid atherosclerosis, left ventricular impairment, and arrhythmias or episodes of myocardial ischemia. 2) Since cardiovascular events may occur in elderly people as a result of health or life circumstances which may have changed in the months preceding the event, the study will contact participants at frequent intervals to evaluate their status with respect to concurrent disease, social support networks, stressful life situations, diet, physical activity and other risk factors. The study has three secondary objectives pertaining to the elderly populations: 1) to evaluate the factors associated with preclinical cardiovascular diseases (such as carotid atherosclerosis, left ventricular impairment and episodes of arrhythmia or myocardial ischemia); 2) to evaluate predictors of disability, institutionalization and mortality to participants who have CHD or stroke; and 3) to measure the utilization and impact of medical care services for CHD and stroke. The contractor shall serve as a Field Center for this study. The duties of the Field Centers include recruitment of an appropriate cohort, conduct interviews and clinical examinations, surveillance of the cohort, and data analysis.