PIMI SUBSTUDY OF THE ASYMPTOMATIC CARDIAC ISCHEMIA PILOT

本项目的目的是进行一项多中心研究， 心理生理因素与症状和 无症状心肌缺血及其治疗。 主要目的是 评估影响神经和心理生理因素， 心肌缺血的临床表现 冠状动脉疾病（CAD）。 另一个目标是评估 不同医疗护理模式和无缺血对 这些特点。 心理生理学研究人群 心肌缺血检查（PIMI）将包括总计225例 从ACIP研究登记处招募的患者。 该人群将 接受详细的神经和心理生理检查， 更全面的心理评估。 这些测试的细节将 根据PIMI制定的最终方案确定 ACIP指导委员会的小组委员会。 这将包括 放射性核素显像的心理生理应激试验，运动 在基线和预定时间进行压力测试和神经系统检查 研究间隔，以便将患者的医疗状况 他或她的治疗结果对心脏病的心理生理学 缺血 本合同修改适用于临床单位， 患者和数据收集。

The purpose of this program is to conduct a multicenter study to evaluate the psychophysiological factors related to both symptomatic and asymptomatic cardiac ischemia and its treatment. The primary objective is to evaluate neurological and psychophysiological factors affecting the manifestation and presentation of myocardial ischemia in patients with coronary artery disease (CAD). An additional objective is to assess the influence of different modes of medical care and freedom from ischemia on these characteristics. The study population for Psychophysiological Investigations of Myocardial Ischemia (PIMI) will consist of a total of 225 patients recruited from the ACIP study registry. This population will undergo detailed neurological and psychophysiological examinations and a more comprehensive psychological evaluation. Details of these tests will be determined according to the final protocol developed by a PIMI subcommittee of the ACIP steering committee. This will include psychophysiological stress testing with radionuclide imaging, exercise stress testing, and neurological examinations at baseline and predetermined intervals of the study, in order to relate the patient's medical condition and outcome of his or her treatment to the psychophysiology of cardiac ischemia. This contract modification is for a Clinical Unit for recruitment of patients and data collection.