The AspiriN To Inhibit SEPSIS (ANTISEPSIS) trial; an ASPREE substudy to measure the benefit of low dose aspirin in the prevention of severe sepsis.

阿司匹林抑制败血症（ANTISEPSIS）试验；

• 批准号: nhmrc : 1041986
• 负责人: A/Pr Robyn Woods
• 金额: $ 27.49万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/aspirin-inhibit-sepsis-severe-sepsis/111425
• 关键词: AspiriN; Inhibit; SEPSIS; ANTISEPSIS; trial

Recent discoveries suggest that low doses of aspirin may save lives in patients with infection by limiting its severity. We will conduct a large-scale primary prevention study using daily low-dose aspirin to explore whether this widely used drug can safely prevent severe infection. This study is made possible by collaborative involvement in an existing Australian and USA funded study called ASPREE. Finding a treatment that helps prevent severe effects and outcomes of infection would be a major health advance.

最近的发现表明，低剂量的阿司匹林可以通过限制其严重程度来挽救感染患者的生命。我们将开展每日低剂量阿司匹林的大规模一级预防研究，探索这种广泛使用的药物是否可以安全预防严重感染。这项研究是由澳大利亚和美国资助的一项名为ASPREE的研究共同参与的。找到一种有助于预防感染的严重影响和后果的治疗方法将是一项重大的健康进步。