PIMI SUBSTUDY OF THE ASYMPTOMATIC CARDIAC ISCHEMIA

该计划的目的是进行一项多中心研究，以评估 与症状性和非症状性的心理生理因素 无症状性心肌缺血及其治疗。主要目标是 评估神经和心理生理学因素对 急性心肌梗死患者心肌缺血的临床表现 冠状动脉疾病。另一个目标是评估 不同医疗救治模式和无脑缺血对心脏功能的影响 这些特点。心理生理学的研究人群 对心肌缺血(PIMI)的调查将包括总共225项 从ACIP研究登记中招募的患者。这些人口将 接受详细的神经和心理生理检查，并 更全面的心理测评。这些测试的详细信息将 根据PIMI制定的最终协议确定 ACIP指导委员会小组委员会。这将包括 用放射性核素成像进行心理生理应激测试，运动 压力测试，以及基线和预定的神经学检查 研究的间隔期，以描述患者的医疗状况 以及他或她的治疗对心脏心理生理学的影响 缺血症。 这份合同修改是为了招聘一个临床单位 患者和数据的收集。

The purpose of this program is to conduct a multicenter study to evaluate the psychophysiological factors related to both symptomatic and asymptomatic cardiac ischemia and its treatment. The primary objective is to evaluate neurological and psychophysiological factors affecting the manifestation and presentation of myocardial ischemia in patients with coronary artery disease (CAD). An additional objective is to assess the influence of different modes of medical care and freedom from ischemia on these characteristics. The study population for Psychophysiological Investigations of Myocardial Ischemia (PIMI) will consist of a total of 225 patients recruited from the ACIP study registry. This population will undergo detailed neurological and psychophysiological examinations and a more comprehensive psychological evaluation. Details of these tests will be determined according to the final protocol developed by a PIMI subcommittee of the ACIP steering committee. This will include psychophysiological stress testing with radionuclide imaging, exercise stress testing, and neurological examinations at baseline and predetermined intervals of the study, in order to relate the patient's medical condition and outcome of his or her treatment to the psychophysiology of cardiac ischemia. This contract modification is for a Clinical Unit for recruitment of patients and data collection.