Estimating use of tobacco and nicotine products through wastewater analysis

通过废水分析估算烟草和尼古丁产品的使用量

• 批准号: LP180100715
• 负责人: Prof Kevin Thomas
• 金额: $ 13.57万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-10-18 至 2023-07-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP180100715
• 关键词: Estimating; use; tobacco; nicotine; products

This project aims to equip the Australian public health and security sector with a tool to accurately measure tobacco consumption in the general population. Specific human biomarkers in urine will be identified using non-target approaches and their pharmacokinetics quantified. The new data will address critical gaps in our knowledge on the population-level excretion of biomarkers for the consumption of tobacco and alternative nicotine products. The outcomes of this project will provide reliable, cost-effective estimates of tobacco consumption for use with wastewater-based epidemiology assessments. This will enable changes in tobacco use to be accurately evaluated for the first time and improve the efficacy of tobacco control measures.

该项目旨在为澳大利亚公共卫生和安全部门提供一种工具，以准确衡量普通人群的烟草消费量。将使用非靶方法鉴定尿液中的特定人类生物标志物，并对其药代动力学进行定量。新数据将解决我们对烟草和替代尼古丁产品消费的生物标志物的人群水平排泄知识的关键差距。该项目的成果将提供可靠的、具有成本效益的烟草消费估计数，用于基于废水的流行病学评估。这将使烟草使用的变化首次得到准确评估，并提高烟草控制措施的效力。