SIXTH INTERNATIONAL WORKSHOP ON PLASMINOGEN ACTIVATION

这是一项支持1997年Vith International的提案 纤溶酶原分子和细胞生物学研讨会 激活。纤溶酶原激活(PA)仍然是核心 心脏、肺和血液疾病的治疗重点，以及 纤溶酶原激活剂药物已成为 心肌梗死、中风等疾病的治疗 血栓栓塞性疾病。因此，PA的研究是在界面上进行的 科学研究、临床医学和生物技术。 基础实验室的贡献尤其突出 对这一领域的新疗法的开发具有重要意义。这个 PA研讨会为调查人员提供了一个独特的机会 来自世界各地的人在小范围内互动交流思想 所有参与者都居住的非正式环境。 这一系列PA研讨会的一个独特之处在于，他们有 过去和今后都将主要是抽象驱动的会议。 因此，与大多数其他会议相比，最令人兴奋的 目前在外地的工作将被强调，并将是漫长的 将避免审查已经发布的数据。爆炸品 对这一领域的兴趣导致了第一个PA的组织 1987年举办的讲习班以及第一次会议和随后的半年期会议 会议得到了与会者的好评和好评 取得了巨大的成功。第VIth PA研讨会将在 加州科罗拉多州，1997年11月1日至6日。部分资助 在此应用程序中请求用于本次会议。给定 科学和临床发展的持续快速发展 PA的领域，因为它与心、肺、脑、 肾脏等，这次会议应该再一次非常合适 而且是及时的。这次会议将有一个独特的重点，因为它将 重视PA在生理和病理生理中的作用 除溶栓外，还需进行其他过程。其中包括神经性的 功能、动脉粥样硬化、血管生成、血管生成、肥胖和 癌症，并将汇聚对生物学感兴趣的科学家， PA的生物化学和遗传学。我们预计，广泛的 本次会议将进行的互动和讨论将 帮助确定重要的新方向、新问题和 未来研究的技术。

This is a proposal to support the 1997 VITH International Workshop on Molecular and Cellular Biology of Plasminogen Activation. Plasminogen activation (PA) continues to be a central focus for therapeutic in heart, lung, and blood diseases, and plasminogen activator pharmaceuticals have become a mainstay for the treatment of myocardial infarction, stroke, and other thromboembolic disorders. The study of PA thus is at the interface of scientific research, clinical medicine, and biotechnology. Contributions from the basic laboratory have been particularly important for the development of new therapies in this field. The PA Workshop has provided an unique opportunity for investigators from around the world to interact and exchange ideas in a small informal environment in which all participants are in residence. One unique aspect of this series of PA Workshops is that they have been and will continue to be primarily abstract-driven meetings. Therefore, and in contrast to most other meetings, the most exciting and current work in the field will be emphasized, and lengthy reviews of already published data will be avoided. The explosive interest in this field led to the organization of the first PA Workshop in 1987 and the initial meeting and subsequent biannual meetings have been well attended and regarded by the participants as resounding successes. The VIth PA Workshop will be held in Coronado, California from November 1-6, 1997. Partial funding for this meeting is requested in this application. Given the continued rapid pace of scientific and clinical developments in the field of PA as it pertains to diseases of the heart, lung, brain, kidneys, etc., this meeting should again be extremely appropriate and timely. This meeting will have an unique focus in that it will emphasize the role of PA in physiological and pathophysiological processes in addition to thrombolysis. These include neural functions, atherogenesis, angiogenesis, vasculogenesis, obesity and cancer, and will bring together scientists interested in the biology, biochemistry and genetics of PA. We anticipate that the extensive interactions and discussions which will occur at this meeting will help to identify important new directions, problems, and technologies for future research.