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SANDIMMUNE AND OG37 325 IN PREVENTION OF RENAL ALLOGRAFT REJECTION

SANDIMMUNE AND OG37 325 IN PREVENTION OF RENAL ALLOGRAFT REJECTION
SANDIMUNE 和 OG37 325 预防肾同种异体移植排斥
批准号：
5216169
负责人：
ALAN B LEICHTMAN
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5216169
关键词：
clearance rate clinical research cyclosporines cytochrome P450 drug screening /evaluation enzyme activity human subject human therapy evaluation kidney function kidney transplantation transplant rejection

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中文摘要
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英文摘要
This protocol provided for the determination of iothalamate and iohexol renal clearances and hepatic cytochrome P450 3A enzyme activity in patients participating in a phase-III multicenter trial comparing the safety and efficacy of the cyclosporin analog, OG 37-325, to that of cyclosporin A in recipients of first renal transplants.
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