Wavelength Modulated Raman Spectroscopy for Applications in Healthcare

波长调制拉曼光谱在医疗保健中的应用

• 批准号: 700644
• 金额: $ 3.18万
• 依托单位: M-SQUARED LASERS LIMITED
• 依托单位国家: 英国
• 项目类别: GRD Proof of Market
• 财政年份: 2016
• 资助国家: 英国
• 起止时间: 2016 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=700644
• 关键词: Wavelength; Modulated; Raman; Spectroscopy; Applications

Almost from its discovery there have been grand hopes for Raman spectroscopy to be aubiquitous tool for chemical analysis. It has the potential to identify substances easily anddistinctly from fingerprint-like spectra. This can be done with simple photonic architecture,allowing for potential portable and miniaturised form factors. Unfortunately theoverwhelming fluorescence background common to all analytes obscures the weak Ramansignal and thus makes this dream unrealised. Finally wavelength modulated Ramanspectroscopy (WMRS) represents an innovative solution that delivers fast, fluorescence-freeRaman spectra. WMRS has a wide range of potential applications in the healthcare industryfrom discriminating between cancerous and healthy tissue, to determining drug concentrationsin biological liquids and identifying the presence of inflammation and infection as well as aanalytical technique for high throughput screening. This market study will aim to clarify theoptimum development pathway for this technology in the healthcare sector.

几乎从它的发现，人们就对拉曼光谱作为化学分析的万能工具寄予厚望。它有可能从指纹图谱中简单而清晰地识别物质。这可以通过简单的光子架构来完成，从而允许潜在的便携式和可扩展的形状因子。不幸的是，所有分析物共有的压倒性荧光背景掩盖了微弱的拉曼信号，从而使这个梦想无法实现。最后，波长调制拉曼光谱（WMRS）代表了一种创新的解决方案，提供快速，无荧光拉曼光谱。WMRS在医疗保健行业具有广泛的潜在应用，从区分癌组织和健康组织，到确定生物液体中的药物浓度，以及识别炎症和感染的存在，以及用于高通量筛选的分析技术。这项市场研究旨在阐明该技术在医疗保健领域的最佳发展途径。