ROSS LABORATORIES MULTIPLE INVESTIGATOR STUDY OF GROWTH TOLERANCE AND PLASMA

罗斯实验室多位研究者对生长耐受性和血浆的研究

• 批准号: 6244223
• 负责人: STEPHEN B DOWTON
• 金额: $ 2.25万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-01-06 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6244223
• 关键词: baby food; clinical research; developmental nutrition; diet therapy; dietary aminoacid; human subject; infant human (0-1 year); nutrient requirement; phenylketonurias

Despite reasonable clinical experience with mixtures of L-amino acids in the management of Phenylketonuria (PKU), L-amino acids which are the source of approximately 75% of dietary protein equivalent in this condition have not been systematically studied to determine their efficacy in supporting longterm growth and in maintaining normal amino acid profiles. This study is an attempt to evaluate the ability of L-amino acid mixtures such as that of the Ross Metabolic Formula System (RMFS) to support normal nutritional status of infants with PKU.

尽管 L-氨基酸混合物具有合理的临床经验 苯丙酮尿症（PKU）的管理，L-氨基酸是 约 75% 膳食蛋白质当量的来源 尚未对病情进行系统研究以确定其疗效 支持长期生长和维持正常氨基酸 配置文件。 本研究试图评估 L-氨基的能力 酸性混合物，例如罗斯代谢公式系统 (RMFS) 的酸性混合物 支持 PKU 婴儿的正常营养状况。