Novel DNA fingerprinting apparatus:Portable,Ultra-Rapid and single base pair resolution

该项目将生产和评估适用于诊断、分离和检测长度仅相差一个碱基对的DNA靶标的原型消耗品。大量的基因测试依赖于DNA分子之间的多态，包括DNA Afingerprint。市场上提供的标准试剂盒涉及使用专家操作员和昂贵的实验室设备。Biogene之前已经通过新颖的化学和仪器在大规模多重检测领域展示并申请了专利保护。拟议的研究将探索如何改进这种方法的解决方案，使更低成本、简化的消耗品既可以在实验室使用，也可以在市场上使用，如取证、人类基因组和细菌病原体分型。

This project will produce and evaluate protype consumables suitable for the diagnosticseparation and detection of DNA targets differing by only a single base pair in length. A largenumber of genetic tests rely on polymorphisms between DNA molecules, including DNAfingerprinting. The standard kits available on the marketplace involve the use of expertoperators and expensive laboratory equipment. BioGene has previously demonstrated andapplied for patent protection in the field of massive multiplexed detection, via novelchemistries and apparatus. The proposed research will investigate means of improving theresolution of this approach to the point where a lower cost, simplified consumable could beused in both the laboratory but also the field in markets such as forensics, human genomicsand bacterial pathogen typing.BioGene(BG),BG Research(BGR)