Novel DNA fingerprinting apparatus:Portable,Ultra-Rapid and single base pair resolution

新型DNA指纹仪：便携式、超快速、单碱基对分辨率

• 批准号: 710470
• 金额: $ 12.74万
• 依托单位: B G RESEARCH LIMITED
• 依托单位国家: 英国
• 项目类别: GRD Proof of Concept
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=710470
• 关键词: Novel; DNA; fingerprinting; apparatus; Portable

This project will produce and evaluate protype consumables suitable for the diagnosticseparation and detection of DNA targets differing by only a single base pair in length. A largenumber of genetic tests rely on polymorphisms between DNA molecules, including DNAfingerprinting. The standard kits available on the marketplace involve the use of expertoperators and expensive laboratory equipment. BioGene has previously demonstrated andapplied for patent protection in the field of massive multiplexed detection, via novelchemistries and apparatus. The proposed research will investigate means of improving theresolution of this approach to the point where a lower cost, simplified consumable could beused in both the laboratory but also the field in markets such as forensics, human genomicsand bacterial pathogen typing.BioGene(BG),BG Research(BGR)

该项目将生产和评估原型耗材，适用于DNA靶标的诊断、分离和检测，只有一个碱基对的长度差异。大量的基因测试依赖于DNA分子之间的多态性，包括DNA指纹。市场上可获得的标准试剂盒涉及使用专家操作人员和昂贵的实验室设备。BioGene之前已经在大规模多路检测领域展示并申请了专利保护，通过新的化学物质和设备。拟议的研究将调查提高这种方法的分辨率的方法，使成本更低，简化的消耗品既可以用于实验室，也可以用于市场领域，如法医学，人类基因组学和细菌病原体分型。BioGene (BG)、BG研究(BGR)