RECOVERY FROM TRAUMATIC BRAIN INJURY IN CHILDREN

儿童脑外伤的康复

• 批准号: 2039052
• 负责人: Hudson Taylor
• 金额: $ 43.02万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-15 至 2001-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2039052
• 关键词: brain injury; child (0-11); clinical research; family structure /dynamics; functional ability; human subject; longitudinal human study; outcomes research; quality of life; rehabilitation; trauma

Children who sustain moderate-to-severe traumatic brain injury (TBI) are at high risk for long-term neurobehavioral sequelae. Little is known, however, about the impact of pediatric TBI on families, or the extent to which recovery from TBI is influenced by the family environment. The purpose of the proposed continuation project is to fill this void through extended follow-up of a sample of children who were hospitalizes between the ages of 6-12 years for either TBI or orthopedic injuries not involving CNS insult. The original study was designed to follow children and families over the first post-injury year. Hypothesis 1 was that TBI in this age group has more adverse and enduring effects on families than orthopedic injuries. Hypothesis 2 was that characteristics of the family environment predict child outcomes, even after injury severity and the child's pre-injury behavioral functioning are taken into account. Preliminary findings support both hypotheses and raise questions with regard to the later, adolescent outcomes of TBI compared to orthopedic injuries. In the proposed project, the majority of current study participants will return for three extended follow-up spaced at one-year intervals. The sample will include 41 children and adolescents with severe TBI, 47 with moderate TBI, and 54 with orthopedic injuries. although previous measures will be readministered and hypotheses are unchanged, additional tests of executive function and social reasoning will be given to the children to investigate later-emerging deficits in these areas. Assessments of family outcomes will also be expanded to include measures of sibling adjustment, daily phone diaries of family activities, and direct observations of parent-child interactions. Analysis will focus on group comparisons, changes over time, and predictors of outcome. Results will clarify injury sequelae, shed light on risk and protective factors, and inform efforts to reduce the long-term morbidity of TBI and other traumatic childhood injures.

遭受中度至重度创伤性脑损伤（TBI）的儿童 有长期神经行为后遗症的高风险 我们所知甚少， 然而，关于儿童TBI对家庭的影响，或 TBI的恢复受家庭环境的影响。 的 拟议的延续项目的目的是填补这一空白 通过对住院儿童样本的长期随访， 年龄在6-12岁之间的TBI或骨科损伤， 包括中枢神经系统损伤。 最初的研究旨在遵循 在受伤后的第一年，孩子和家庭。 假设1是 在这个年龄组中，TBI对 家庭比骨科受伤。 假设二是， 家庭环境的特征可以预测孩子的结果，甚至 受伤后的严重程度和儿童受伤前的行为功能 被考虑在内。 初步研究结果支持这两种假设 并提出了关于TBI的后期青少年后果的问题 与骨科损伤相比。 在计划中，大多数 的当前研究参与者将返回进行三次延长随访 间隔一年 样本将包括41名儿童， 严重TBI的青少年，47例中度TBI，54例 骨科损伤 尽管先前的措施将重新被考虑， 假设不变，执行功能的额外测试， 社会推理将给予孩子们调查 在这些领域出现的不足。 家庭结局评估 还将扩大到包括兄弟姐妹调整措施，每天 家庭活动的电话日记，以及对 亲子互动 分析将侧重于组间比较， 随着时间的推移而变化，以及结果的预测因素。 结果将澄清 伤害后遗症，揭示风险和保护因素，并告知 努力减少TBI和其他创伤性疾病的长期发病率， 童年伤害