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INTRAVENOUS POTASSIUM EFFECTS ON QUINIDINE INDUCED REPOLARIZATION CHANGE

INTRAVENOUS POTASSIUM EFFECTS ON QUINIDINE INDUCED REPOLARIZATION CHANGE
静脉注射钾对奎尼丁诱导的复极化变化的影响
批准号：
6246756
负责人：
DAN M RODEN
金额：
$3.1万
依托单位：
VANDERBILT UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-01-27 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6246756
关键词：
clinical research electrocardiography heart electrical activity heart function human subject intravenous administration pharmacokinetics potassium quinidine

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中文摘要
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英文摘要
We will test the hypothesis that quinidine-induced changes in QT interval are blunted by elevation of serum potassium. Prolongation of cardiac repolarization, which is manifest on the surface electro- cardiogram as an increase in the QT interval, has been viewed as a desirable mode of antiarrhythnic drug action.
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