TRANSPLANTATION OF FETAL SUBSTANTIA NIGRA INTO CAUDATE NUCLEUS AND PUTAMEN

将胎儿黑质移植到尾状核和壳核

• 批准号: 6247075
• 负责人: DENNIS D SPENCER
• 金额: $ 2.68万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6247075
• 关键词: Parkinson's disease; adult human (21+); caudate nucleus; clinical research; embryo /fetus tissue transplantation; human fetus tissue; human subject; human therapy evaluation; nervous system transplantation; neurochemistry; outcomes research; postoperative state; substantia nigra

The purpose of the study is to establish the safety and efficacy of transplanting human fetal substantia nigra into the caudate nucleus of adult patients with Parkinson's Disease and to determine whether any changes found in neurological function correlate with evidence of graft survival, neurochemical function and intergration with the host brain.

本研究的目的是确定 将人胎儿黑质移植到小脑尾状核内， 成年帕金森病患者，并确定是否有任何 神经功能变化与移植物相关 存活、神经化学功能和与宿主大脑的整合。